# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1054936 | P | Octanol-water partition coefficient, log D at pH 7.0 by HPLC method | 24 | small-molecule physicochemical format | Scientific Literature | |||
2. | ALA1054937 | B | Inhibition of ACAT in Japanese White rabbit liver microsomes | Oryctolagus cuniculus | 39 | microsome format | Scientific Literature | ||
3. | ALA1054938 | F | Anti-foam cell formation activity in human THP1 cells assessed as inhibition of esterified cholesterol accumulation after 24 hrs in presence of Japanese white rabbit high-cholesterol serum | Homo sapiens | 39 | cell-based format | Scientific Literature | ||
4. | ALA1056531 | B | Ratio of compound IC50 to Pactimibe IC50 for inhibition of ACAT in Japanese White rabbit liver microsomes | Oryctolagus cuniculus | 1 | microsome format | Scientific Literature | ||
5. | ALA1056532 | A | Protein binding in rat plasma assessed as total and protein free fraction concentration at 10 ug/ML after 150 mins by ultracentrifugation method | Rattus norvegicus | 2 | cell-free format | Scientific Literature | ||
6. | ALA1056533 | F | Anti-foam cell formation activity in human THP1 cells assessed as inhibition of esterified cholesterol accumulation after 24 hrs in presence of albumin | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
7. | ALA1056534 | F | Inhibition of hepatic cholesterol secretion in ICR mouse at 10 mg/kg, po after 3 hrs by enzymatic method | Mus musculus | 2 | organism-based format | Scientific Literature | ||
8. | ALA1056535 | A | Cmax in Sprague-Dawley rat at 10 mg/kg, po | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
9. | ALA1056536 | A | Tmax in Sprague-Dawley rat at 10 mg/kg, po | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
10. | ALA1056537 | A | Half life in Sprague-Dawley rat at 10 mg/kg, po | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
11. | ALA1056538 | A | AUC (0 to 24 hrs) in Sprague-Dawley rat at 10 mg/kg, po | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
12. | ALA5243723 | B | Inhibition of rabbit liver microsome ACAT | Oryctolagus cuniculus | 2 | microsome format | Scientific Literature | ||
13. | ALA5243724 | F | Inhibition of accumulation of esterified cholesterol in human THP-1 cells | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
14. | ALA5243725 | P | Lipophilicity, logD of the compound at pH 7 | 2 | small-molecule physicochemical format | Scientific Literature |