| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1026899 | B | Displacement of [125I]ovine-CRF from CRF1 receptor in rat frontal cortex by rapid filtration technique | Rattus norvegicus | 40 | tissue-based format | Scientific Literature | ||
| 2. | ALA1030150 | B | Displacement of [125I]Tyr-ovine-CRF from CRF1 receptor in rat frontal cortex homogenate by gamma counting | Rattus norvegicus | 49 | tissue-based format | Scientific Literature | ||
| 3. | ALA1030151 | B | Displacement of [125I]sauvagine from CRF2 receptor in pig choroid plexus homogenate by gamma counting | Sus scrofa | 2 | tissue-based format | Scientific Literature | ||
| 4. | ALA1030152 | P | Octanol-water partition coefficient, log D at pH 7.4 | 1 | small-molecule physicochemical format | Scientific Literature | |||
| 5. | ALA1030153 | F | Antagonist activity at CRF1 receptor in human Y79 cells assessed as inhibition of CRF-stimulated cAMP production by HTRF method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA1030154 | F | Agonist activity at CRF1 receptor in human Y79 cells assessed as CRF-stimulated cAMP production at 10 uM by HTRF method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA1030155 | A | Clearance in Sprague-Dawley rat at 2 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 8. | ALA1030156 | A | Volume of distribution at steady state in Sprague-Dawley rat at 2 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 9. | ALA1030157 | A | Half life in Sprague-Dawley rat at 2 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 10. | ALA1030158 | A | AUC in Sprague-Dawley rat at 10 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 11. | ALA1030159 | A | Cmax in Sprague-Dawley rat at 10 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 12. | ALA1030160 | A | Oral bioavailability in Sprague-Dawley rat at 10 mg/kg | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 13. | ALA1030161 | A | Hepatic blood flow in Sprague-Dawley rat at 2 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 14. | ALA1030162 | A | Clearance in cynomolgus monkey at 2 mg/kg, iv | Macaca fascicularis | 1 | organism-based format | Scientific Literature | ||
| 15. | ALA1030163 | A | Volume of distribution at steady state in cynomolgus monkey at 2 mg/kg, iv | Macaca fascicularis | 1 | organism-based format | Scientific Literature | ||
| 16. | ALA1030164 | A | Half life in cynomolgus monkey at 2 mg/kg, iv | Macaca fascicularis | 1 | organism-based format | Scientific Literature | ||
| 17. | ALA1030165 | A | AUC in cynomolgus monkey at 10 mg/kg, po | Macaca fascicularis | 1 | organism-based format | Scientific Literature | ||
| 18. | ALA1030166 | A | Cmax in cynomolgus monkey at 10 mg/kg, po | Macaca fascicularis | 1 | organism-based format | Scientific Literature | ||
| 19. | ALA1030167 | A | Oral bioavailability in cynomolgus monkey at 10 mg/kg | Macaca fascicularis | 1 | organism-based format | Scientific Literature | ||
| 20. | ALA1030168 | A | Plasma concentration in Sprague-Dawley rat at 1 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature |
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