# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1816443 | F | Antimigratory activity against human PC3 cells at 50 uM after 24 hrs by wound healing assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
2. | ALA1816444 | F | Antiproliferative activity against human MDA-MB-231 cells at 5 to 50 uM after 24 hrs by MTT assay | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
3. | ALA1816446 | F | Antiproliferative activity against human PC3 cells at 5 to 50 uM after 24 hrs by MTT assay | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
4. | ALA1026212 | B | Reduction in human pancreatic recombinant 1B PLA2 activity expressed in Escherichia coli assessed as hydrolysis of 1,2-dimyristoyl-sn-3-glycerophosphocholine vesicles at 0.03 mol fraction relative to cholate | Homo sapiens | 18 | assay format | Scientific Literature | ||
5. | ALA1026996 | B | Reduction in human pancreatic recombinant 1B PLA2 activity expressed in Escherichia coli assessed as hydrolysis of 1,2-dimyristoyl-sn-3-glycerophosphocholine vesicles at 0.007 mol fraction relative to cholate | Homo sapiens | 18 | assay format | Scientific Literature | ||
6. | ALA1027008 | F | Agonist activity at human FXR transfected in human HuH7 cells co-transfected with human BSEP promoter reporter plasmid at 10 uM after 30 hrs by dual-luciferase reporter assay relative to control | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
7. | ALA1027009 | F | Antagonist activity at human FXR transfected in human HuH7 cells co-transfected with human BSEP promoter reporter plasmid at 10 uM after 30 hrs by dual-luciferase reporter assay relative to chenodeoxycholate | Homo sapiens | 10 | cell-based format | Scientific Literature |