# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4613052 | B | Inhibition of HIF1 transactivation activity in HEK293T cells transfected with pGL3-5HRE-VEGF-luciferase at 0.01 to 1 uM incubated for 24 hrs under hypoxia condition by luciferase reporter gene assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
2. | ALA4613053 | F | Antitumor activity against mouse LLC cells allografted in C57BL/6J mouse assessed as inhibition of tumor growth at 5 mg/kg, ip dosed every 3 days for 17 days starting from 2 days after inoculation relative to control | Mus musculus | 2 | organism-based format | Scientific Literature | ||
3. | ALA4613054 | F | Antitumor activity against mouse LLC cells allografted in C57BL/6J mouse assessed as inhibition of tumor growth at 5 mg/kg, ip dosed every 3 days for 17 days starting from 2 days after inoculation and co-treated with 5 mg/kg, ip EGFR inhibitor gefitinib relative to control | Mus musculus | 1 | organism-based format | Scientific Literature | ||
4. | ALA4613055 | F | Antitumor activity against mouse LLC cells allografted in C57BL/6J mouse assessed as reduction tumor weight at 5 mg/kg, ip dosed every 3 days for 17 days starting from 2 days after inoculation relative to control | Mus musculus | 2 | organism-based format | Scientific Literature | ||
5. | ALA4613056 | F | Antitumor activity against mouse LLC cells allografted in C57BL/6J mouse assessed as reduction of tumor weight at 5 mg/kg, ip dosed every 3 days for 17 days starting from 2 days after inoculation and co-treated with 5 mg/kg, ip EGFR inhibitor gefitinib relative to control | Mus musculus | 1 | organism-based format | Scientific Literature | ||
6. | ALA4613057 | T | Toxicity in C57BL/6J mouse allografted with mouse LLC cells assessed as effect on body weight at 5 mg/kg, ip dosed every 3 days for 17 days starting from 2 days after inoculation | Mus musculus | 1 | organism-based format | Scientific Literature | ||
7. | ALA4613058 | T | Toxicity in C57BL/6J mouse allografted with mouse LLC cells assessed as effect on body weight at 5 mg/kg, ip dosed every 3 days for 17 days starting from 2 days after inoculation and co-treated with 5 mg/kg, ip EGFR inhibitor gefitinib | Mus musculus | 1 | organism-based format | Scientific Literature |