# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1057866 | Binding | Displacement of [125I]-(D-Tyr0)NMB from human neuromedin B receptor transfected in HEK293 cells | Homo sapiens | 34 | ALA1152392 | cell-based format | Scientific Literature | |
2. | ALA1057868 | Binding | Ratio of benzodiazepine IC50 to compound IC50 for human neuromedin B receptor transfected in HEK293 cells | Homo sapiens | 1 | ALA1152392 | cell-based format | Scientific Literature | |
3. | ALA1057869 | ADME | Cytotoxicity against HEK293 cells up to 30 uM after 72 hrs by alamar blue assay | Homo sapiens | 1 | ALA1152392 | cell-based format | Scientific Literature | |
4. | ALA1057870 | ADME | Cytotoxicity against human HeLa cells up to 30 uM after 72 hrs by alamar blue assay | Homo sapiens | 1 | ALA1152392 | cell-based format | Scientific Literature | |
5. | ALA1057871 | ADME | Cytotoxicity against human HeLa cells after 72 hrs by alamar blue assay | Homo sapiens | 1 | ALA1152392 | cell-based format | Scientific Literature | |
6. | ALA1057872 | Functional | Antagonist activity at human neuromedin B receptor transfected in HEK293 cells assessed as inhibition of 1 nM neuromedin B-induced myo-[3H]inositol phosphate accumulation after 60 mins by scintillation proximity assay | Homo sapiens | 2 | ALA1152392 | cell-based format | Scientific Literature | |
7. | ALA1057873 | Functional | Ratio of benzodiazepine IC50 to compound IC50 for antagonist activity at human neuromedin B receptor transfected in HEK293 cells assessed as inhibition of 1 mM neuromedin B-induced myo-[3H]inositol phosphate accumulation | Homo sapiens | 1 | ALA1152392 | cell-based format | Scientific Literature |