| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1051116 | F | Inhibition of hemozoin formation after 48 hrs in chloroquine-sensitive Plasmodium falciparum NF54 | Plasmodium falciparum NF54 | 7 | assay format | Scientific Literature | ||
| 2. | ALA1051117 | F | Inhibition of hemozoin formation after 48 hrs in multi drug-resistant Plasmodium yoelii | Plasmodium yoelii | 7 | assay format | Scientific Literature | ||
| 3. | ALA1051119 | F | Antiplasmodial activity after 48 hrs against chloroquine-sensitive Plasmodium falciparum NF54 by [3H]hypoxanthine uptake | Plasmodium falciparum | 7 | organism-based format | Scientific Literature | ||
| 4. | ALA1051120 | F | Antiplasmodial activity as increased heme accumulation after 48 hrs against chloroquine-sensitive Plasmodium falciparum NF54 at 10-100 uM by spectrophotometry | Plasmodium falciparum | 3 | organism-based format | Scientific Literature | ||
| 5. | ALA1051121 | F | Induction of oxidative stress as decreased glutathione after 48 hrs in chloroquine-sensitive Plasmodium falciparum NF54 by TCA assay | Plasmodium falciparum | 3 | organism-based format | Scientific Literature | ||
| 6. | ALA1051122 | F | Induction of oxidative stress as lipid peroxide formation after 48 hrs in chloroquine-sensitive Plasmodium falciparum NF54 | Plasmodium falciparum | 3 | organism-based format | Scientific Literature | ||
| 7. | ALA1051123 | F | Induction of oxidative stress as increased H2O2 formation after 48 hrs in chloroquine-sensitive Plasmodium falciparum NF54 by spectrofluorimetry | Plasmodium falciparum | 3 | organism-based format | Scientific Literature | ||
| 8. | ALA1051124 | F | Induction of oxidative stress as increased hydroxyl radical formation after 48 hrs in chloroquine-sensitive Plasmodium falciparum NF54 by fast blue BB assay | Plasmodium falciparum | 3 | organism-based format | Scientific Literature | ||
| 9. | ALA1051125 | F | Antiplasmodial activity as decreased mitochondrial transmembrane potential after 1 hrs against multi drug-resistant Plasmodium yoelii trophozoite infected Swiss mice (Mus musculus) erythrocytes at 10 uM by JC1 uptake | Plasmodium yoelii | 2 | organism-based format | Scientific Literature | ||
| 10. | ALA1051126 | F | Antiplasmodial activity after 48 hrs against chloroquine-sensitive Plasmodium falciparum NF54 by [3H]hypoxanthine uptake in presence of PBN | Plasmodium falciparum | 1 | organism-based format | Scientific Literature | ||
| 11. | ALA1051127 | F | Antiplasmodial activity after 48 hrs against chloroquine-sensitive Plasmodium falciparum NF54 by [3H]hypoxanthine uptake in presence of mannitol | Plasmodium falciparum | 1 | organism-based format | Scientific Literature | ||
| 12. | ALA1051128 | F | Antiplasmodial activity as parasite growth after 24 hrs against chloroquine-sensitive Plasmodium falciparum NF54 infected human B+ erythrocytes at <40 uM 24 hrs preinfection by [3H]hypoxanthine uptake | Plasmodium falciparum | 2 | organism-based format | Scientific Literature | ||
| 13. | ALA1051129 | A | Cytotoxicity against human MCF7 cells assessed as cell viability at 10 to 1000 uM after 24 hrs by MTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 14. | ALA1051130 | F | Selectivity index ratio of IC50 for human MCF7 cells to IC50 for chloroquine-sensitive Plasmodium falciparum NF54 | 3 | cell-based format | Scientific Literature | |||
| 15. | ALA1051131 | F | Antiplasmodial activity as reduced parasitaemia at day 4 against multi drug-resistant Plasmodium yoelii infected BALB/c mice (Mus musculus) at 10 mg/kg intraperitoneal dose 6 hrs post infection and daily for 3 days by Giemsa stain | Plasmodium yoelii | 2 | organism-based format | Scientific Literature | ||
| 16. | ALA1051132 | F | Antiplasmodial activity as reduced parasitaemia at day 4 against multi drug-resistant Plasmodium yoelii infected BALB/c mice (Mus musculus) at 25 mg/kg intraperitoneal dose 6 hrs post infection and daily for 3 days by Giemsa stain | Plasmodium yoelii | 3 | organism-based format | Scientific Literature | ||
| 17. | ALA1051133 | F | Antiplasmodial activity as reduced parasitaemia at day 4 against multi drug-resistant Plasmodium yoelii infected BALB/c mice (Mus musculus) at 50 mg/kg intraperitoneal dose 6 hrs post infection and daily for 3 days by Giemsa stain | Plasmodium yoelii | 3 | organism-based format | Scientific Literature | ||
| 18. | ALA1051135 | F | Inhibition of hemozoin formation after 48 hrs against chloroquine-sensitive Plasmodium falciparum NF54 at 10 to 100 uM by spectrophotometry | Plasmodium falciparum NF54 | 3 | assay format | Scientific Literature | ||
| 19. | ALA1051136 | A | Cytotoxicity against human MCF7 cells assessed as cell viability after 24 hrs by MTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 20. | ALA1051137 | F | Antiplasmodial activity as parasite invasion after 24 hrs against chloroquine-sensitive Plasmodium falciparum NF54 infected human B+ erythrocytes at <40 uM 24 hrs preinfection by [3H]hypoxanthine uptake | Plasmodium falciparum | 1 | organism-based format | Scientific Literature |
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