| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1062746 | B | Inhibition of ALK5 expressed in CHO cells assessed as inhibition of TGF-beta-induced Smad2 phosphorylation at 1 uM | 40 | ALA1154039 | cell-based format | Scientific Literature | ||
| 2. | ALA1062749 | F | Cytotoxicity against human embryo lung fibrosis cells at 30 uM by MTT assay | Homo sapiens | 41 | ALA1154039 | cell-based format | Scientific Literature | |
| 3. | ALA1062750 | B | Inhibition of ALK4 expressed in baculovirus/Sf9 cells assessed as inhibition of receptor autophosphorylation at 0.1 uM after 3 hrs | 14 | ALA1154039 | cell-based format | Scientific Literature | ||
| 4. | ALA1062751 | B | Inhibition of ALK4 expressed in baculovirus/Sf9 cells assessed as inhibition of receptor autophosphorylation at 1 uM after 3 hrs | 14 | ALA1154039 | cell-based format | Scientific Literature | ||
| 5. | ALA1062752 | B | Inhibition of ALK5 expressed in baculovirus/Sf9 cells assessed as inhibition of receptor autophosphorylation at 0.1 uM after 3 hrs | 14 | ALA1154039 | cell-based format | Scientific Literature | ||
| 6. | ALA1062753 | B | Inhibition of ALK5 expressed in baculovirus/Sf9 cells assessed as inhibition of receptor autophosphorylation at 1 uM after 3 hrs | 14 | ALA1154039 | cell-based format | Scientific Literature | ||
| 7. | ALA1062754 | B | Inhibition of ALK7 expressed in baculovirus/Sf9 cells assessed as inhibition of receptor autophosphorylation at 0.1 uM after 3 hrs | 14 | ALA1154039 | cell-based format | Scientific Literature | ||
| 8. | ALA1056764 | B | Inhibition of ALK7 expressed in baculovirus/Sf9 cells assessed as inhibition of receptor autophosphorylation at 1 uM after 3 hrs | 14 | ALA1154039 | cell-based format | Scientific Literature | ||
| 9. | ALA1056765 | B | Selectivity for ALK5 over ALK4 | 2 | ALA1154039 | assay format | Scientific Literature | ||
| 10. | ALA1056766 | B | Selectivity for ALK5 over ALK7 | 2 | ALA1154039 | assay format | Scientific Literature | ||
| 11. | ALA2437532 | B | Inhibition of TGFbeta-induced downstream transcriptional activation of ALK5 (unknown origin) expressed in CHO-HIR cells assessed as intracellular translocation of EGFP-Smad2 at 1 uM after 2 hrs by luciferase assay | Homo sapiens | 15 | ALA2434835 | cell-based format | Scientific Literature |
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