# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1027768 | ADME | Volume of distribution at steady state in human at 5.5 mg, iv administered as bolus dose | Homo sapiens | 1 | ALA1158480 | organism-based format | Scientific Literature | |
2. | ALA1027769 | ADME | Clearance in human at 5.5 mg, iv administered as bolus dose | Homo sapiens | 1 | ALA1158480 | organism-based format | Scientific Literature | |
3. | ALA1028556 | ADME | Volume of distribution in human at 5.5 mg, iv administered as bolus dose | Homo sapiens | 1 | ALA1158480 | organism-based format | Scientific Literature | |
4. | ALA3854386 | ADME | Oral bioavailability in human | Homo sapiens | 1 | ALA3853299 | organism-based format | Scientific Literature | |
5. | ALA2090300 | Functional | Antiplatelet activity against rabbit platelets assessed as inhibition of thrombin-induced platelet aggregation | Oryctolagus cuniculus | 9 | ALA2086305 | cell-based format | Scientific Literature | |
6. | ALA2090301 | Functional | Antithrombotic activity in Sprague-Dawley rat venous thrombosis model assessed as thrombus dry weight administered via gastric tube qd for 3 days after 4 hrs of last post dose | Rattus norvegicus | 4 | ALA2086305 | organism-based format | Scientific Literature | |
7. | ALA2090302 | Functional | Antiplatelet activity against rabbit platelets assessed as inhibition of ADP-induced platelet aggregation | Oryctolagus cuniculus | 3 | ALA2086305 | cell-based format | Scientific Literature | |
8. | ALA2349999 | Functional | Antithrombotic activity in intragastrically dosed rat venous thrombosis model | Rattus norvegicus | 2 | ALA2346620 | organism-based format | Scientific Literature | |
9. | ALA2350000 | Binding | Binding affinity to human thrombin | Homo sapiens | 1 | ALA2346620 | single protein format | Scientific Literature | |
10. | ALA2350001 | Functional | Inhibition of ADP-induced rabbit platelet aggregation compound pre-incubated in rabbit liver microsomal suspension | Oryctolagus cuniculus | 3 | ALA2346620 | microsome format | Scientific Literature | |
11. | ALA2350002 | Functional | Inhibition of thrombin-induced rabbit platelet aggregation compound pre-incubated in rabbit liver microsomal suspension | Oryctolagus cuniculus | 8 | ALA2346620 | microsome format | Scientific Literature | |
12. | ALA2421876 | ADME | Oral bioavailability in human | Homo sapiens | 2 | ALA2417538 | organism-based format | Scientific Literature | |
13. | ALA2421878 | ADME | Oral bioavailability in rat | Rattus norvegicus | 4 | ALA2417538 | organism-based format | Scientific Literature | |
14. | ALA2421879 | Physicochemical | Aqueous solubility of the compound at pH 9.0 | 1 | ALA2417538 | small-molecule physicochemical format | Scientific Literature | ||
15. | ALA2421880 | Physicochemical | Aqueous solubility of the compound at pH 6.3 | 1 | ALA2417538 | small-molecule physicochemical format | Scientific Literature | ||
16. | ALA2421881 | Physicochemical | Aqueous solubility of the compound at pH 7.4 | 1 | ALA2417538 | small-molecule physicochemical format | Scientific Literature | ||
17. | ALA2421888 | Physicochemical | Distribution coefficient, log D of the compound at pH 7 by potentiometric titration | 4 | ALA2417538 | small-molecule physicochemical format | Scientific Literature | ||
18. | ALA3096454 | Functional | Antithrombotic activity in CD rat wire coil model assessed as fold loss of blood at ED80, po administered 30 to 90 mins before thromboplastin relative to control | Rattus norvegicus | 3 | ALA3091444 | organism-based format | Scientific Literature | |
19. | ALA3096458 | Functional | Antithrombotic activity in po dosed CD rat wire coil model assessed as reduction of protein content administered 30 to 90 mins before thromboplastin | Rattus norvegicus | 3 | ALA3091444 | organism-based format | Scientific Literature | |
20. | ALA3419502 | Functional | Inhibition of thrombin-induced platelet aggregation in Sprague-Dawley rat at 3 mg/ml administered for 4 days relative to control | Rattus norvegicus | 3 | ALA3414490 | organism-based format | Scientific Literature |