# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2034623 | B | Activity of N-terminus hexaHis-tagged human TNSK2 expressed in Escherichia coli BL21 (DE3) cells using biotinylated NAD+ as substrate after 90 mins by Western blot analysis | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
2. | ALA1032002 | B | Inhibition of Wnt3 expressed in mouse L-cells assessed as inhibition of Wnt/catanin signaling pathway by luciferase reporter gene assay | 50 | cell-based format | Scientific Literature | |||
3. | ALA1268408 | B | Induction of Axin2 in mouse L cell expressing Wnt and STF assessed as decreased beta-casein level by Western blot method | Mus musculus | 1 | cell-based format | Scientific Literature | ||
4. | ALA1268411 | B | Induction of Axin2 stabilization in human DLD1 cells assessed as inhibition of Wnt/beta-casein pathway | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
5. | ALA1267306 | F | Inhibition of caudal fin regeneration after mechanical resection in zebrafish at 10 uM after 7 days | Danio rerio | 9 | organism-based format | Scientific Literature | ||
6. | ALA1267307 | B | Inhibition of Wnt3A mediated fgf20a expression in Zebrafish resected tail fins after 24 hrs post amputation | Danio rerio | 2 | assay format | Scientific Literature | ||
7. | ALA2384487 | B | Inhibition of 6XHis-tagged tankyrase1 (1091 to 1325) (unknown origin) after 60 mins in presence of NAD | Homo sapiens | 32 | single protein format | Scientific Literature | ||
8. | ALA4303805 | F | Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of Caco-2 cells at 10 uM after 48 hours by high content imaging | Homo sapiens | 5,612 | organism-based format | SARS-CoV-2 Screening Data 2020-21 | ||
9. | ALA4495582 | F | SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response from peptide substrate | Severe acute respiratory syndrome coronavirus 2 | 7,212 | assay format | SARS-CoV-2 Screening Data 2020-21 | ||
10. | ALA4513082 | F | Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging | Chlorocebus sabaeus | 7,212 | organism-based format | SARS-CoV-2 Screening Data 2020-21 | ||
11. | ALA4616003 | B | Inhibition of full length human C-terminal His-tagged PARP1 expressed in baculovirus infected Sf9 cells at 200 uM using chicken core histone as substrate incubated for 20 mins followed by [32P[-NAD+ addition and further incubated for 1 hr by liquid scintillation counter relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
12. | ALA4616005 | B | Inhibition of full length human N-terminal His-tagged PARP2 expressed in baculovirus infected Sf9 cells at 200 uM using histone H3.3 as substrate incubated for 20 mins followed by [32P[-NAD+ addition and further incubated for 1 hr by liquid scintillation counter | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
13. | ALA4616006 | B | Inhibition of full length human N-terminal GST-tagged TNKS1 ADP-ART catalytic domain (1001 to 1327 residues) using histone H2A as substrate incubated for 20 mins followed by [32P[-NAD+ addition and further incubated for 1 hr by liquid scintillation counter | Homo sapiens | 8 | single protein format | Scientific Literature | ||
14. | ALA4616008 | B | Inhibition of full length human N-terminal GST-tagged TNKS2 ADP-ART catalytic domain (1001 to 1327 residues) using histone H2A as substrate incubated for 20 mins followed by [32P[-NAD+ addition and further incubated for 1 hr by liquid scintillation counter | Homo sapiens | 8 | single protein format | Scientific Literature | ||
15. | ALA4616014 | F | Inhibition of colony formation in human DLD1 cells at 1 uM incubated for 12 days by crystal violet staining based assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
16. | ALA4808149 | B | Enzymatic assay of human HDAC6 with commercial peptide substrate | Homo sapiens | 5,603 | single protein format | Fraunhofer HDAC6 | ||
17. | ALA4808150 | B | Enzymatic assay of human HDAC6 with custom peptide substrate | Homo sapiens | 5,603 | single protein format | Fraunhofer HDAC6 |