# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA619789 | B | Inhibitory activity against 5-hydroxytryptamine 3 receptor in rat cortical membranes using [3H]- 1-Methyl-1H-indazole-3-carboxylic acid (8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-amide as a radioligand | 8 | cell membrane format | Scientific Literature | |||
2. | ALA617717 | F | Inhibition of 5-HT evoked reflex bradycardia in rat. | 20 | organism-based format | Scientific Literature | |||
3. | ALA857503 | F | Evaluated for the 5-hydroxytryptamine 4 receptor antagonistic activity in piglet atrium model | 6 | tissue-based format | Scientific Literature | |||
4. | ALA620594 | F | Antagonistic activity evaluated by ability to block serotonin induced relaxation (mediated by activation of 5-hydroxytryptamine 4 receptor) in carbamylcholine (10e-6 M) contracted esophagus at a concentration of 10e-5 M. | Rattus norvegicus | 8 | tissue-based format | Scientific Literature | ||
5. | ALA619645 | B | pKi value for inhibition of [3H]LY-278584 binding to 5-hydroxytryptamine 3 receptor | Rattus norvegicus | 9 | protein complex format | Scientific Literature | ||
6. | ALA618045 | F | Evaluated for the 5-hydroxytryptamine 3 receptor antagonistic activity in Bezold-Jarisch model expressed as inhibition of the reflex bradycardia induced by an intravenous injection | 6 | assay format | Scientific Literature | |||
7. | ALA783820 | F | The compound was evaluated for the inhibition of the von Bezold-Jarisch reflex in rat administered intravenously | Rattus norvegicus | 5 | assay format | Scientific Literature | ||
8. | ALA783821 | F | The compound was evaluated for the inhibition of the von Bezold-Jarisch reflex in rat administered orally | Rattus norvegicus | 4 | assay format | Scientific Literature | ||
9. | ALA846696 | F | Selectivity ratio of peroral vs intravenous delivery | Rattus norvegicus | 4 | assay format | Scientific Literature |