# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1052341 | Functional | Antibacterial activity against permeabilized polA-deficient Bacillus anthracis Sterne assessed as inhibition of DNA replication by cell based assay | Bacillus anthracis | 18 | ALA1152954 | organism-based format | Scientific Literature | |
2. | ALA1052342 | Functional | Antibacterial activity against Bacillus anthracis Sterne by broth microdilution method | Bacillus anthracis | 18 | ALA1152954 | organism-based format | Scientific Literature | |
3. | ALA1052343 | Functional | Antibacterial activity against Staphylococcus aureus Smith by broth microdilution method | Staphylococcus aureus | 18 | ALA1152954 | organism-based format | Scientific Literature | |
4. | ALA1052344 | Binding | Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assay | Staphylococcus aureus | 18 | ALA1152954 | single protein format | Scientific Literature | |
5. | ALA1052345 | Binding | Inhibition of Bacillus anthracis DNA helicase DnaB expressed in Escherichia coli BL21 (DE3) assessed as strand unwinding after 30 mins by FRET assay | Bacillus anthracis | 36 | ALA1152954 | assay format | Scientific Literature | |
6. | ALA1052346 | Functional | Antibacterial activity against Bacillus stearothermophilus ATCC 12980 by broth microdilution method | Geobacillus stearothermophilus | 3 | ALA1152954 | organism-based format | Scientific Literature | |
7. | ALA1052347 | Functional | Antibacterial activity against Bacillus subtilis BD54 by broth microdilution method | Bacillus subtilis | 3 | ALA1152954 | organism-based format | Scientific Literature | |
8. | ALA1052348 | Functional | Antibacterial activity against Staphylococcus aureus ATCC 25923 by broth microdilution method | Staphylococcus aureus | 3 | ALA1152954 | organism-based format | Scientific Literature | |
9. | ALA1052349 | Functional | Antibacterial activity against Enterococcus faecalis ATCC 29212 by broth microdilution method | Enterococcus faecalis | 3 | ALA1152954 | organism-based format | Scientific Literature | |
10. | ALA1052350 | Functional | Antibacterial activity against vancomycin-resistant Enterococcus faecalis ATCC 51575 by broth microdilution method | Enterococcus faecalis | 3 | ALA1152954 | organism-based format | Scientific Literature | |
11. | ALA1052351 | Functional | Antibacterial activity against Bacillus megaterium ATCC 12872 by broth microdilution method | Priestia megaterium | 3 | ALA1152954 | organism-based format | Scientific Literature | |
12. | ALA1052352 | Functional | Antibacterial activity against Bacillus licheniformis ATCC 14580 by broth microdilution method | Bacillus licheniformis | 3 | ALA1152954 | organism-based format | Scientific Literature | |
13. | ALA1052353 | Functional | Antibacterial activity against Bacillus thuringiensis ATCC 10792 by broth microdilution method | Bacillus thuringiensis | 3 | ALA1152954 | organism-based format | Scientific Literature | |
14. | ALA1052354 | Functional | Antibacterial activity against pXO2- and AXN-deficient Bacillus anthracis Ames harboring pXO1 gene by broth microdilution method | Bacillus anthracis | 3 | ALA1152954 | organism-based format | Scientific Literature | |
15. | ALA1052355 | Functional | Antibacterial activity against Bacillus cereus ATCC 4342 by broth microdilution method | Bacillus cereus | 3 | ALA1152954 | organism-based format | Scientific Literature | |
16. | ALA1052356 | Functional | Antibacterial activity against pXO2-deficient Bacillus anthracis Weybridge harboring pXO1 gene by broth microdilution method | Bacillus anthracis | 3 | ALA1152954 | organism-based format | Scientific Literature | |
17. | ALA1052357 | Functional | Antibacterial activity against pXO2-deficient Bacillus anthracis Ames 35 harboring pXO1 gene by broth microdilution method | Bacillus anthracis | 3 | ALA1152954 | organism-based format | Scientific Literature | |
18. | ALA1052358 | ADME | Cytotoxicity against human HeLa cells by MTT assay | Homo sapiens | 18 | ALA1152954 | cell-based format | Scientific Literature | |
19. | ALA1052366 | Binding | Inhibition of Bacillus subtilis DNA gyrase up to 50 uM by gel mobility assay | Bacillus subtilis | 3 | ALA1152954 | assay format | Scientific Literature | |
20. | ALA1053870 | Functional | Antibacterial activity against methicillin-resistant Staphylococcus aureus isolate 1094 by broth microdilution method | Staphylococcus aureus | 3 | ALA1152954 | organism-based format | Scientific Literature |