# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1058996 | B | Inhibition of human RNase H assessed as substrate cleavage by fluorescence assay | Homo sapiens | 12 | ALA1153542 | single protein format | Scientific Literature | |
2. | ALA1058997 | B | Inhibition of HIV1 recombinant reverse transcriptase p66/p51 heterodimer in presence of Mg2+ | Human immunodeficiency virus 1 | 12 | ALA1153542 | assay format | Scientific Literature | |
3. | ALA3088594 | F | Antiviral activity against HIV1 3B/LAI infected in human MT-4 cells assessed as inhibition of virus-induced cytopathic effect measured survival after 5 days by MTT assay | Human immunodeficiency virus 1 | 13 | ALA3085743 | organism-based format | Scientific Literature | |
4. | ALA3088595 | F | Antiviral activity against HIV1 3B infected in human HeLa cells expressing CD4 assessed as inhibition of viral replication after 2 days by beta-galactosidase reporter gene assay | Human immunodeficiency virus 1 | 52 | ALA3085743 | organism-based format | Scientific Literature | |
5. | ALA3088597 | B | Inhibition of strand transfer activity of recombinant HIV1 integrase using 5'-end-labeled 21-mer double-stranded DNA as substrate after 60 mins by electrochemiluminescent plate-based assay | Human immunodeficiency virus 1 | 52 | ALA3085743 | single protein format | Scientific Literature | |
6. | ALA3088598 | B | Inhibition of RNase H activity of recombinant HIV1 reverse transcriptase using poly(dC)-[3H]poly(rG) as substrate | Human immunodeficiency virus 1 | 49 | ALA3085743 | single protein format | Scientific Literature | |
7. | ALA3418915 | B | Inhibition of HIV-1 recombinant RT-associted RNase H activity expressed in Escherichia coli M15 using poly(dC)-[3H]poly(rG) hybrid as substrate | Human immunodeficiency virus 1 | 28 | ALA3414482 | assay format | Scientific Literature | |
8. | ALA3418916 | B | Inhibition of HIV-1 integrase strand transfer activity by gel-based assay | Human immunodeficiency virus 1 | 28 | ALA3414482 | single protein format | Scientific Literature | |
9. | ALA3418917 | F | Antiviral activity against HIV-1 3B infected in human HeLa-CD4-LTR-beta-gal cells after 1 day by spectroscopic analysis | Human immunodeficiency virus 1 | 26 | ALA3414482 | organism-based format | Scientific Literature |