# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1058191 | B | Displacement of rhodamine-labeled probe from human soluble epoxide hydrolase by fluorescence polarization assay | Homo sapiens | 25 | single protein format | Scientific Literature | ||
2. | ALA1058192 | B | Displacement of rhodamine-labeled probe from rat soluble epoxide hydrolase by fluorescence polarization assay | Rattus norvegicus | 25 | single protein format | Scientific Literature | ||
3. | ALA1058193 | B | Inhibition of human soluble epoxide hydrolase in human HepG cells assessed as conversion of epoxyeicosatienoic acid to dihydroxyeicosatrienoic acid after 30 mins by ELISA | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
4. | ALA1058194 | A | Metabolic stability in human liver microsomes assessed as half life by LC-MS/MS analysis in presence of NADPH | Homo sapiens | 19 | microsome format | Scientific Literature | ||
5. | ALA1058195 | A | Metabolic stability in rat liver microsomes assessed as half life by LC-MS/MS analysis in presence of NADPH | Rattus norvegicus | 19 | microsome format | Scientific Literature | ||
6. | ALA1058199 | A | Plasma concentration in Sprague-Dawley rat at 5 mg/kg, po after 4 hrs by LC-MS/MS analysis | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
7. | ALA1058202 | A | Inhibition of CYP2C9 | 3 | single protein format | Scientific Literature | |||
8. | ALA1058203 | A | Inhibition of CYP2C19 | 3 | single protein format | Scientific Literature | |||
9. | ALA1058985 | A | Inhibition of CYP2J2 | 3 | single protein format | Scientific Literature | |||
10. | ALA3301363 | P | ASTRAZENECA: Octan-1-ol/water (pH7.4) distribution coefficent measured by a shake flask method described in J. Biomol. Screen. 2011, 16, 348-355. Experimental range -1.5 to 4.5 | 4,197 | small-molecule physicochemical format | AstraZeneca Deposited Data | |||
11. | ALA5228408 | B | Inhibition of human sEH | Homo sapiens | 2 | single protein format | Scientific Literature |