| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1038573 | B | Inhibition of rat alpha-glucosidase assessed as p-nitrophenol release at 50 ug/ml | Rattus norvegicus | 15 | ALA1154076 | assay format | Scientific Literature | |
| 2. | ALA1038575 | F | Antioxidant activity assessed as DPPH radical scavenging activity | 15 | ALA1154076 | assay format | Scientific Literature | ||
| 3. | ALA3583454 | F | Anti-neuroinflammatory activity against mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess assay | Mus musculus | 30 | ALA3580603 | cell-based format | Scientific Literature | |
| 4. | ALA3583455 | A | Cytotoxicity against mouse BV2 cells assessed as reduction of cell viability at IC50 after 24 hrs by MTT assay | Mus musculus | 30 | ALA3580603 | cell-based format | Scientific Literature | |
| 5. | ALA4675227 | B | Selectivity ratio IC50 for inhibition of human CYP1B1 expressed in sacchrosomes toIC50 for Inhibition of CYP1A1 expressed in sacchrosomes | Homo sapiens | 1 | ALA4673221 | assay format | Scientific Literature | |
| 6. | ALA4675228 | B | Selectivity ratio IC50 for inhibition of human CYP1A2 expressed in sacchrosomes toIC50 for Inhibition of CYP1A1 expressed in sacchrosomes | Homo sapiens | 1 | ALA4673221 | assay format | Scientific Literature | |
| 7. | ALA4675229 | B | Selectivity ratio IC50 for inhibition of human CYP1B1 expressed in HEK293 cells toIC50 for Inhibition of CYP1A1 expressed in HEK293 cells | Homo sapiens | 2 | ALA4673221 | cell-based format | Scientific Literature | |
| 8. | ALA4675230 | B | Inhibition of human CYP1A1 expressed in HEK293 cells assessed as reduction in CYP1A1 mediated B[alpha]P-7,8- dihydrodiol induced-toxicity by measuring EC50 at 3 times of IC50 concentration by MTT assay relative to control | Homo sapiens | 4 | ALA4673221 | cell-based format | Scientific Literature | |
| 9. | ALA4675234 | F | Induction of cellular senescence in human MCF7 cells over expressing CYP1A assessed as increase in beta-gal-positive cells at 2 times of EC50 concentration incubated for 96 hrs by microscopic assay relative to control | Homo sapiens | 2 | ALA4673221 | cell-based format | Scientific Literature | |
| 10. | ALA4675235 | F | Induction of cell cycle arrest in human MCF7 over expressing CYP1A cells assessed as accumulation at G2/M phase incubated for 24 hrs by PI staining based flow cytometric analysis (Rvb = 22.6%) | Homo sapiens | 3 | ALA4673221 | cell-based format | Scientific Literature | |
| 11. | ALA4675236 | F | Induction of cell cycle arrest in human MCF7 over expressing CYP1A cells assessed as accumulation at S phase incubated for 24 hrs by PI staining based flow cytometric analysis (Rvb = 20.1%) | Homo sapiens | 3 | ALA4673221 | cell-based format | Scientific Literature | |
| 12. | ALA4675237 | F | Induction of cell cycle arrest in human MCF7 over expressing CYP1A cells assessed as accumulation at G0/G1 phase incubated for 24 hrs by PI staining based flow cytometric analysis (Rvb =54.3 %) | Homo sapiens | 3 | ALA4673221 | cell-based format | Scientific Literature | |
| 13. | ALA4675238 | F | Cell cycle arrest in human MCF-7 cells over expressing CYP1A1 assessed as down regulation of CyclinD1 after 24 hrs by western blotting assay | Homo sapiens | 3 | ALA4673221 | cell-based format | Scientific Literature | |
| 14. | ALA4675239 | F | Antiproliferative activity against human MCF-7 cells overexpressing CYP1A1 assessed as reduction in cell viability | Homo sapiens | 3 | ALA4673221 | cell-based format | Scientific Literature | |
| 15. | ALA4675240 | B | Inhibition of human CYP1A1 expressed in HEK293 cells assessed as reduction in CYP1A1 mediated B[alpha]P-7,8- dihydrodiol induced-toxicity by measuring EC50 at 3 times of IC50 concentration by MTT assay (Rvb = 1.4 +/ 0.4 uM) | Homo sapiens | 3 | ALA4673221 | cell-based format | Scientific Literature | |
| 16. | ALA4675241 | A | Inhibition of human CYP3A4 expressed in Sacchrosomes using dibenzylfluorescein as substrate by fluorescence based assay | Homo sapiens | 2 | ALA4673221 | assay format | Scientific Literature | |
| 17. | ALA4675242 | A | Inhibition of human CYP2E1 expressed in Sacchrosomes by fluorescence based assay | Homo sapiens | 2 | ALA4673221 | assay format | Scientific Literature | |
| 18. | ALA4675243 | A | Inhibition of human CYP2D6 expressed in Sacchrosomes using 7-ethoxy-methyloxy-3-cyanocoumarin as substrate by fluorescence based assay | Homo sapiens | 2 | ALA4673221 | assay format | Scientific Literature | |
| 19. | ALA4675244 | A | Inhibition of human CYP2C19 expressed in Sacchrosomes using 3-cyano-7-ethoxycoumarin as substrate by fluorescence based assay | Homo sapiens | 2 | ALA4673221 | assay format | Scientific Literature | |
| 20. | ALA4675245 | A | Inhibition of human CYP2C18 expressed in Sacchrosomes by fluorescence based assay | Homo sapiens | 2 | ALA4673221 | assay format | Scientific Literature |
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