# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1044821 | B | Inhibition of Candida albicans DHFR expressed in Escherichia coli BL21 (DE3) assessed as rate of NADPH consumption using dihydrofolate as substrate | Candida albicans | 82 | assay format | Scientific Literature | ||
2. | ALA1044822 | B | Inhibition of human DHFR assessed as rate of NADPH consumption using dihydrofolate as substrate | Homo sapiens | 36 | single protein format | Scientific Literature | ||
3. | ALA1044823 | B | Selectivity index, ratio of IC50 for human DHFR to IC50 for Candida albicans DHFR | 36 | assay format | Scientific Literature | |||
4. | ALA1044824 | F | Antifungal activity against Candida albicans by alamar blue assay | Candida albicans | 35 | organism-based format | Scientific Literature | ||
5. | ALA1044825 | A | Cytotoxicity against human MCF10A cells after 4 hrs by alamar blue assay | Homo sapiens | 35 | cell-based format | Scientific Literature | ||
6. | ALA1272639 | B | Inhibition of wild type Bacillus anthracis recombinant DHFR | Bacillus anthracis | 18 | single protein format | Scientific Literature | ||
7. | ALA1272640 | B | Inhibition of Bacillus anthracis recombinant DHFR F96I mutant | Bacillus anthracis | 18 | assay format | Scientific Literature | ||
8. | ALA1272641 | B | Selectivity ratio of Ki for wild type Bacillus anthracis recombinant DHFR to Ki for Bacillus anthracis recombinant DHFR F96I mutant | Bacillus anthracis | 18 | assay format | Scientific Literature | ||
9. | ALA1272642 | B | Inhibition of Bacillus anthracis recombinant DHFR Y102F mutant | Bacillus anthracis | 18 | assay format | Scientific Literature | ||
10. | ALA1272643 | B | Selectivity ratio of Ki for wild type Bacillus anthracis recombinant DHFR to Ki for Bacillus anthracis recombinant DHFR Y102F mutant | Bacillus anthracis | 18 | assay format | Scientific Literature |