#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA1057686	Binding	Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assay	Homo sapiens	47	ALA1154666	assay format	Scientific Literature
2.	ALA1057688	Binding	Inhibition of human glutaminyl cyclase overexpressed in HEK293 cells coexpressing amyloid precursor protein assessed as reduction in pGlu-Abeta-3(pE)-40,42 peptide formation at 1 uM relative to 1-(3-(1H-imidazol-1-yl)propyl)-3-(3,4-dimethoxyphenyl)thiourea	Homo sapiens	18	ALA1154666	cell-based format	Scientific Literature
3.	ALA2395921	Binding	Inhibition of human glutaminyl cyclase expressed in HEK293 cells using L-glutaminyl-beta-naphthylamine as substrate after 1 hr by fluorometric analysis	Homo sapiens	42	ALA2390817	cell-based format	Scientific Literature
4.	ALA4009734	Physicochemical	Permeability, logPe of the compound after 4 hrs by PAMPA		4	ALA4007443	small-molecule physicochemical format	Scientific Literature
5.	ALA4009735	Binding	Inhibition of mouse glutaminyl cyclase assessed as reduction in conversion of H-Gln-AMC hydrobromide to pGlu-AMC preincubated with substrate for 10 mins followed by enzyme addition by pGAPase coupled fluorometry	Mus musculus	2	ALA4007443	single protein format	Scientific Literature
6.	ALA4009736	Binding	Inhibition of human glutaminyl cyclase assessed as reduction in conversion of H-Gln-AMC hydrobromide to pGlu-AMC preincubated with substrate for 10 mins followed by enzyme addition by pGAPase coupled fluorometry	Homo sapiens	53	ALA4007443	single protein format	Scientific Literature
7.	ALA4009739	ADME	Cytotoxicity against mouse HT22 cells assessed as cell viability at 10 uM after 18 hrs by MTT assay	Mus musculus	9	ALA4007443	cell-based format	Scientific Literature
8.	ALA4009740	Functional	Antialzheimer activity in human amyloid beta (3 to 40) induced acute ICR mouse Alzheimer's disease mouse model assessed as inhibition of amyloid beta (N3pE to 40) formation in brain at 10 mM, icv by sandwich ELISA	Mus musculus	9	ALA4007443	assay format	Scientific Literature
9.	ALA4009741	Functional	Antialzheimer activity in human amyloid beta (3 to 40) induced acute ICR mouse Alzheimer's disease mouse model assessed as inhibition of amyloid beta (N3pE to 40) formation in brain at 25 mg/kg, ip by sandwich ELISA	Mus musculus	4	ALA4007443	organism-based format	Scientific Literature
10.	ALA4376103	Binding	Inhibition of recombinant human N-terminal His6-tagged glutaminyl cyclase (Ala33 to Leu361 residues) expressed in baculovirus infected Sf21 insect cells using H-Gln-AMC hydrobromide as substrate measured in presence of pGAPase by fluorometric assay	Homo sapiens	68	ALA4373720	cell-based format	Scientific Literature
11.	ALA5035499	Binding	Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetry	Homo sapiens	92	ALA5034025	single protein format	Scientific Literature
12.	ALA5249644	Binding	Inhibition of human glutaminyl cyclase using L-glutamine-7-amido-4-methylcoumarin as substrate incubated for 10 mins in presence of pyroglutamyl peptidase by fluorometry analysis	Homo sapiens	35	ALA5247605	single protein format	Scientific Literature