| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1063822 | F | Reduction in cholesterol level in lysosomal storage organelles of NPC1 deficient chinese hamster CT43 cells at 10 uM by LSO compartment ratio assay | Cricetulus griseus | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA1063823 | F | Reduction in cholesterol level in lysosomal storage organelles of NPC1 deficient chinese hamster CT60 cells at 10 uM by LSO compartment ratio assay | Cricetulus griseus | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA1063824 | F | Inhibition of LDL endocytosis in NPC1 deficient chinese hamster CT60 cells assessed as ratio of DiI-labeled LDL level in treated to untreated control at 10 uM after 35 mins by fluorimetry | Cricetulus griseus | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA1042316 | F | Inhibition of LDL endocytosis in wild type chinese hamster 25RA cells assessed as ratio of DiI-labeled LDL level in treated to untreated control at 10 uM after 35 mins by fluorimetry | Cricetulus griseus | 1 | assay format | Scientific Literature | ||
| 5. | ALA1042317 | F | Inhibition of LDL endocytosis in NPC1 deficient chinese hamster CT60 cells assessed as ratio of DiI-labeled LDL level in treated to untreated control at 10 uM after 18 hrs by fluorimetry | Cricetulus griseus | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA1042318 | F | Inhibition of LDL endocytosis in NPC1 deficient chinese hamster 25RA cells assessed as ratio of DiI-labeled LDL level in treated to untreated control at 10 uM after 18 hrs by fluorimetry | Cricetulus griseus | 1 | assay format | Scientific Literature | ||
| 7. | ALA1042319 | B | Increase in ACAT-induced cholesterol esterification in NPC1 deficient chinese hamster CT60 cells assessed as ratio of [14C]oleic acid incorporation in treated to untreated control at 10 uM | Cricetulus griseus | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA1042320 | F | Effect on cholesterol esters content in NPC1 deficient chinese hamster CT60 cells assessed as ratio of cholesteryl esters level in treated to untreated control at 10 uM by gas chromatography | Cricetulus griseus | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA1042321 | F | Increase in cholesterol efflux in NPC1 deficient chinese hamster CT60 cells at 10 uM after 18 hrs by [3H]cholesterol incorporation assay | Cricetulus griseus | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA1042322 | F | Increase in cholesterol efflux in wild type chinese hamster 25RA cells with SCAP gene gain of function mutation at 10 uM after 18 hrs by [3H]cholesterol incorporation assay | Cricetulus griseus | 1 | assay format | Scientific Literature | ||
| 11. | ALA1042323 | F | Increase in cholesterol efflux in chinese hamster TRVb1 cells expressing human transferrin receptor at 10 uM after 18 hrs by [3H]cholesterol incorporation assay | Cricetulus griseus | 1 | assay format | Scientific Literature | ||
| 12. | ALA1777341 | B | Inhibition of human microsomal PGES1 in cell-free system assessed as inhibition of conversion of PGH2 to PGE2 by HPLC assay | Homo sapiens | 27 | assay format | Scientific Literature | ||
| 13. | ALA1777342 | B | Inhibition of human microsomal PGES1 in cell-free system assessed as inhibition of conversion of PGH2 to PGE2 at 10 uM by HPLC assay relative to control | Homo sapiens | 10 | assay format | Scientific Literature | ||
| 14. | ALA1777343 | B | Inhibition of human recombinant 5-LO in cell-free system assessed as inhibition of LTB4 production at 10 uM after 10 mins by RP-HPLC assay relative to control | Homo sapiens | 9 | single protein format | Scientific Literature | ||
| 15. | ALA1777433 | B | Inhibition of human recombinant 5-LO in cell-free system assessed as inhibition of LTB4 production after 10 mins by RP-HPLC assay | Homo sapiens | 10 | single protein format | Scientific Literature | ||
| 16. | ALA1777434 | B | Inhibition of 5-LO in human polymorphonuclear leukocytes assessed as inhibition of LTB4 production at 10 uM after 10 mins by RP-HPLC assay relative to control | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 17. | ALA1777435 | B | Inhibition of 5-LO in human polymorphonuclear leukocytes assessed as inhibition of LTB4 production after 10 mins by RP-HPLC assay | Homo sapiens | 10 | cell-based format | Scientific Literature |
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