| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1048318 | B | Inhibition of mPGES1 expressed in human HeLa cells assessed as inhibition of IL-1-beta/TNF-alpha-induced PGE2 production at 30 uM by Western blot analysis | Homo sapiens | 3 | ALA1154757 | cell-based format | Scientific Literature | |
| 2. | ALA1048319 | B | Inhibition of mPGES1 expressed in human HeLa cells assessed as inhibition of IL-1-beta/TNF-alpha-induced PGE2 production by Western blot analysis | Homo sapiens | 39 | ALA1154757 | cell-based format | Scientific Literature | |
| 3. | ALA1048320 | B | Inhibition of bovine COX1 at 1 uM | Bos taurus | 1 | ALA1154757 | single protein format | Scientific Literature | |
| 4. | ALA1048321 | B | Inhibition of human recombinant COX2 at 1 uM | Homo sapiens | 1 | ALA1154757 | single protein format | Scientific Literature | |
| 5. | ALA1048322 | B | Inhibition of bovine COX1 at 10 uM | Bos taurus | 1 | ALA1154757 | single protein format | Scientific Literature | |
| 6. | ALA1046625 | B | Inhibition of bovine COX1 at 30 uM | Bos taurus | 1 | ALA1154757 | single protein format | Scientific Literature | |
| 7. | ALA1046626 | B | Inhibition of human recombinant COX2 at 10 uM | Homo sapiens | 1 | ALA1154757 | single protein format | Scientific Literature | |
| 8. | ALA1046627 | B | Inhibition of human recombinant COX2 at 30 uM | Homo sapiens | 1 | ALA1154757 | single protein format | Scientific Literature | |
| 9. | ALA2050885 | B | Inhibition of mPGES-1 derived from IL1beta and TNFalpha stimulated human HeLa cells microsomal fraction using PGH2 as substrate at 1 uM preincubated for 30 mins prior to substrate addition measured after 1 min by LC-MS/MS analysis relative to control | Homo sapiens | 25 | ALA2046422 | cell-based format | Scientific Literature | |
| 10. | ALA2050886 | B | Inhibition of mPGES-1 derived from IL1beta and TNFalpha stimulated human HeLa cells microsomal fraction using PGH2 as substrate preincubated for 30 mins prior to substrate addition measured after 1 min by LC-MS/MS analysis | Homo sapiens | 9 | ALA2046422 | cell-based format | Scientific Literature | |
| 11. | ALA2050887 | B | Inhibition of mPGES-1 derived from LPS stimulated mouse RAW264.7 cells microsomal fraction using PGH2 as substrate at 1 uM preincubated for 30 mins prior to substrate addition measured after 1 min by LC-MS/MS analysis relative to control | Mus musculus | 9 | ALA2046422 | cell-based format | Scientific Literature | |
| 12. | ALA2050888 | B | Inhibition of mPGES-1 derived from LPS stimulated mouse NIH3T3 cells microsomal fraction using PGH2 as substrate at 1 uM preincubated for 30 mins prior to substrate addition measured after 1 min by LC-MS/MS analysis relative to control | Mus musculus | 9 | ALA2046422 | cell-based format | Scientific Literature | |
| 13. | ALA2050889 | B | Inhibition of ovine COX1-mediated PGE2 synthesis using PGH2 as substrate at 1 uM by LC-MS/MS analysis relative to control | Ovis aries | 9 | ALA2046422 | single protein format | Scientific Literature | |
| 14. | ALA2050890 | B | Inhibition of human recombinant COX2-mediated PGE2 synthesis using PGH2 as substrate at 1 uM by LC-MS/MS analysis relative to control | Homo sapiens | 9 | ALA2046422 | single protein format | Scientific Literature | |
| 15. | ALA2050892 | B | Inhibition of mPGES-1 in IL1beta and TNFalpha-stimulated human HeLa cells assessed as PGE2 level after 24 hrs by LC-MS/MS analysis | Homo sapiens | 10 | ALA2046422 | cell-based format | Scientific Literature | |
| 16. | ALA2050895 | B | Inhibition of COX1 in human whole blood assessed as residual TXB2 level at 10 uM after 1 hr by LC-MS/MS analysis relative to control | Homo sapiens | 8 | ALA2046422 | single protein format | Scientific Literature | |
| 17. | ALA2050896 | B | Inhibition of COX1 in human whole blood assessed as residual PGD2 level at 10 uM after 1 hr by LC-MS/MS analysis relative to control | Homo sapiens | 8 | ALA2046422 | single protein format | Scientific Literature | |
| 18. | ALA2050899 | B | Inhibition of COX2 in LPS-stimulated human whole blood assessed as residual PGE2 level at 100 uM preincubated for 15 mins prior to LPS-stimulation measured after 24 hrs by LC-MS/MS analysis relative to control | Homo sapiens | 8 | ALA2046422 | single protein format | Scientific Literature | |
| 19. | ALA2050900 | B | Inhibition of 5-lipoxygenase/FLAP in calcium ionophore-stimulated human whole blood assessed as residual LTB4 level at 10 uM preincubated for 15 mins prior to calcium ionophore-stimulation measured after 15 mins by LC-MS/MS analysis | Homo sapiens | 8 | ALA2046422 | protein complex format | Scientific Literature | |
| 20. | ALA2050901 | B | Inhibition of COX2 in LPS-stimulated human whole blood assessed as residual PGF2alpha level at 100 uM preincubated for 15 mins prior to LPS-stimulation measured after 24 hrs by LC-MS/MS analysis relative to control | Homo sapiens | 8 | ALA2046422 | single protein format | Scientific Literature |
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