# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1047183 | Binding | Inhibition of human PKCtheta by IMAP fluorescence polarization technology | Homo sapiens | 19 | ALA1156015 | single protein format | Scientific Literature | |
2. | ALA1047184 | Binding | Inhibition of PKCdelta by IMAP fluorescence polarization technology | 19 | ALA1156015 | single protein format | Scientific Literature | ||
3. | ALA1047191 | Binding | Inhibition of PKCtheta in C57BL/6 mouse T cells assessed as inhibition of anti-CD3 and anti-CD28-induced IL2 production after 20 to 24 hrs by ELISA | Mus musculus | 3 | ALA1156015 | cell-based format | Scientific Literature | |
4. | ALA1047192 | Functional | Inhibition of anti-CD3 and anti-CD28-induced IL2 production in PKCtheta knockout mouse after 20 to 24 hrs by ELISA | Mus musculus | 3 | ALA1156015 | organism-based format | Scientific Literature | |
5. | ALA1048057 | ADME | Metabolic stability in Sprague-Dawley rat plasma assessed as conversion to 4-(4-methyl-1H-indol-5-ylamino)-5-(5-(piperazin-1-ylmethyl)benzofuran-2-yl)nicotinonitrile | Rattus norvegicus | 2 | ALA1156015 | cell-free format | Scientific Literature |