# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1042541 | Binding | Inhibition of ERK1/2 phosphorylation in PMA-stimulated human U937 cells at 10 to 50 uM after 3 hrs by Western blotting | Homo sapiens | 6 | ALA1156078 | cell-based format | Scientific Literature | |
2. | ALA1042542 | Binding | Inhibition of Rsk1 phosphorylation in PMA-stimulated human U937 cells at 10 to 50 uM after 3 hrs by Western blotting | Homo sapiens | 12 | ALA1156078 | cell-based format | Scientific Literature | |
3. | ALA1042544 | Binding | Inhibition of Elk1 phosphorylation in PMA-stimulated human U937 cells at 50 uM after 3 hrs by Western blotting | Homo sapiens | 4 | ALA1156078 | cell-based format | Scientific Literature | |
4. | ALA1042545 | Binding | Inhibition of p38 phosphorylation in PMA-stimulated human U937 cells at 50 uM after 3 hrs by Western blotting | Homo sapiens | 5 | ALA1156078 | cell-based format | Scientific Literature | |
5. | ALA1042546 | Binding | Inhibition of MEK phosphorylation | 2 | ALA1156078 | assay format | Scientific Literature | ||
6. | ALA1042547 | Binding | Inhibition of JNK phosphorylation | 2 | ALA1156078 | assay format | Scientific Literature | ||
7. | ALA1047050 | Binding | Inhibition of ERK1/2 phosphorylation in EGF-stimulated human SKOV3 cells | Homo sapiens | 2 | ALA1156078 | cell-based format | Scientific Literature | |
8. | ALA1047051 | Binding | Inhibition of recombinant ERK2-mediated myelin basic protein phosphorylation at 50 uM after 30 mins by SDS-PAGE | 2 | ALA1156078 | single protein format | Scientific Literature | ||
9. | ALA1047052 | Functional | Cytotoxicity against human U937 cells assessed as cell viability up to 30 uM after 24 hrs by MTT assay | Homo sapiens | 2 | ALA1156078 | cell-based format | Scientific Literature | |
10. | ALA1047053 | Functional | Antiproliferative activity human U937 cells by [3H]thymidine incorporation assay | Homo sapiens | 1 | ALA1156078 | cell-based format | Scientific Literature | |
11. | ALA1047054 | Functional | Induction of apoptosis in human U937 assessed as loss of mitochondrial membrane potential after 18 hrs by DiOC6 uptake assay | Homo sapiens | 3 | ALA1156078 | cell-based format | Scientific Literature |