# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1047012 | Functional | Growth inhibition of human Tcf 33.13 cells transiently transfected with pGL3-Tcf4-luc and SV40-R-luc after 24 hrs by luciferase reporter assay | Homo sapiens | 41 | ALA1156802 | assay format | Scientific Literature | |
2. | ALA1047013 | Functional | Growth inhibition of human Tcf22C11 cells transiently transfected with pGL3-Tcf4-luc and SV40-R-luc after 24 hrs by luciferase reporter assay | Homo sapiens | 41 | ALA1156802 | cell-based format | Scientific Literature | |
3. | ALA1047014 | Functional | Growth inhibition of human SV5A8 cells transiently transfected with pGL3-SV40-luc and SV40-R-luc after 24 hrs by luciferase reporter assay | Homo sapiens | 41 | ALA1156802 | cell-based format | Scientific Literature | |
4. | ALA1047015 | Physicochemical | Aqueous solubility at pH 7.4 | 40 | ALA1156802 | small-molecule physicochemical format | Scientific Literature | ||
5. | ALA1047016 | ADME | Metabolic stability in rat liver microsomes assessed as half life | Rattus norvegicus | 39 | ALA1156802 | microsome format | Scientific Literature | |
6. | ALA1047017 | ADME | Membrane permeability by PAMPA | 40 | ALA1156802 | assay format | Scientific Literature | ||
7. | ALA3883062 | ADME | Cytotoxicity against human SV5A8 cells expressing SV40 binding sites driving firefly/renilla luciferase reporter gene after 24 hrs by luminometer | Homo sapiens | 262 | ALA3882728 | cell-based format | Patent Bioactivity Data | |
8. | ALA3883063 | Binding | Inhibition of TCF-4/beta catenin in human Tcf33.13 cells expressing Tcf-4/SV40 binding sites driving firefly luciferase reporter gene after 24 hrs by luminometer | Homo sapiens | 264 | ALA3882728 | cell-based format | Patent Bioactivity Data | |
9. | ALA3883064 | Binding | Inhibition of TCF-4/beta catenin in human Tcf22C11 cells expressing Tcf-4/SV40 binding sites driving firefly luciferase reporter gene after 24 hrs by luminometer | Homo sapiens | 264 | ALA3882728 | cell-based format | Patent Bioactivity Data |