| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1794461 | F | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of RanGTP induced Rango (Ran-regulated importin-beta cargo) - Importin beta complex dissociation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540262] | 21,849 | assay format | PubChem BioAssays | |||
| 2. | ALA1794580 | F | PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] | Plasmodium falciparum | 130,890 | organism-based format | PubChem BioAssays | ||
| 3. | ALA2114788 | F | PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) | Homo sapiens | 103,470 | assay format | PubChem BioAssays | ||
| 4. | ALA2114807 | F | PubChem BioAssay. qHTS Assay to Identify Small Molecule Activators of BRCA1 Expression. (Class of assay: confirmatory) | Homo sapiens | 15,516 | assay format | PubChem BioAssays | ||
| 5. | ALA2114810 | F | PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) | Homo sapiens | 86,035 | assay format | PubChem BioAssays | ||
| 6. | ALA1047043 | B | Inhibition of Mycobacterium tuberculosis H37Rv MetAP1c in presence of 50 uM Fe(2+) by Met-AMC substrate hydrolysis assay | Mycobacterium tuberculosis H37Rv | 8 | assay format | Scientific Literature | ||
| 7. | ALA1047044 | B | Inhibition of Mycobacterium tuberculosis H37Rv MetAP1c in presence of 50 uM Ni(2+) by Met-AMC substrate hydrolysis assay | Mycobacterium tuberculosis H37Rv | 8 | assay format | Scientific Literature | ||
| 8. | ALA1047045 | B | Inhibition of Mycobacterium tuberculosis H37Rv MetAP1c in presence of 50 uM Co(2+) by Met-AMC substrate hydrolysis assay | Mycobacterium tuberculosis H37Rv | 8 | assay format | Scientific Literature | ||
| 9. | ALA1047046 | B | Inhibition of Mycobacterium tuberculosis H37Rv MetAP1c in presence of 50 uM Mn(2+) by Met-AMC substrate hydrolysis assay | Mycobacterium tuberculosis H37Rv | 8 | assay format | Scientific Literature | ||
| 10. | ALA1047047 | B | Inhibition of Mycobacterium tuberculosis MetAP1c expressed in Escherichia coli lacking endogenous MetAP by cell based Met-AMC substrate hydrolysis assay | Mycobacterium tuberculosis | 8 | cell-based format | Scientific Literature | ||
| 11. | ALA1047048 | B | Inhibition of Mycobacterium tuberculosis MetAP1c mediated cell growth of Escherichia coli lacking endogenous MetAP complemented with MtMetAP1c after 72 hrs by resazurin dye reduction method | Mycobacterium tuberculosis | 8 | assay format | Scientific Literature | ||
| 12. | ALA1614166 | B | PubChem BioAssay. qHTS Assay for Inhibitors of MBNL1-poly(CUG) RNA binding. (Class of assay: confirmatory) | 34,209 | single protein format | PubChem BioAssays | |||
| 13. | ALA1613829 | F | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1). (Class of assay: confirmatory) [Related pubchem assays: 594 (Rhodamine region spectral profiling screen), 593 (Fluorescein region spectral profiling screen), 2367 (Probe Development Summary for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1)), 2353 (qHTS Validation Assay for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1))] | Homo sapiens | 4,515 | assay format | PubChem BioAssays | ||
| 14. | ALA2114843 | F | PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory) | Homo sapiens | 68,424 | assay format | PubChem BioAssays | ||
| 15. | ALA2114738 | F | PubChem BioAssay. qHTS for Inhibitors of Glutaminase (GLS). (Class of assay: confirmatory) | Homo sapiens | 15,494 | assay format | PubChem BioAssays | ||
| 16. | ALA2412831 | F | Antibacterial activity against Burkholderia thailandensis E264 assessed as bacterial growth inhibition at 1 mM after 24 hrs by two-fold dilution method relative to DMSO-treated control | Burkholderia thailandensis | 18 | assay format | Scientific Literature | ||
| 17. | ALA2412835 | B | Inhibition of Burkholderia pseudomallei recombinant methionine aminopeptidase 1 using H-Met-Gly-Pro-7-amino-4-methylcoumarin hydrochloride as substrate measured for 10 mins by fluorescence assay in presence of human recombinant DPP4 | Burkholderia pseudomallei | 25 | assay format | Scientific Literature | ||
| 18. | ALA3879299 | F | Antibacterial activity against Rickettsia prowazekii str. Breinl infected with 50:1 multiplicity of infection in CD rat primary pulmonary vascular endothelial cells assessed as restoration of host cell viability by measuring fold reduction in viability at 0.3 to 300 uM measured 72 hrs post infection by WST1 assay relative to control | Rickettsia prowazekii str. Breinl | 5 | cell-based format | Scientific Literature | ||
| 19. | ALA3879300 | B | Inhibition of Rickettsia prowazekii str. Madrid E N-terminal His-tagged methionine aminopeptidase 1A expressed in Escherichia coli BL21(DE3) Rosetta cells using Met-AMC as substrate preincubated for 1 hr followed by substrate addition measured after 30 mins for 90 mins in presence of MnCl2 by fluorescence assay | Rickettsia prowazekii str. Madrid E | 26 | cell-based format | Scientific Literature | ||
| 20. | ALA3879303 | F | Antibacterial activity against Rickettsia prowazekii str. Breinl infected in CD rat primary pulmonary vascular endothelial cells assessed as protection against bacterial infection by measuring restoration of host cell viability at 0.3 to 300 uM measured 72 hrs post infection by WST1 assay | Rickettsia prowazekii str. Breinl | 7 | cell-based format | Scientific Literature |
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