# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1037931 | F | Agonist activity at CD11b/CD18 expressed in K562 cells assessed as increase in cell adhesion to fibrinogen | 21 | ALA1156138 | cell-based format | Scientific Literature | ||
2. | ALA4430904 | B | Inhibition of human EAAT1 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake at 10 uM incubated for 5 mins by liquid scintillation counting method | Homo sapiens | 1 | ALA4428119 | cell-based format | Scientific Literature | |
3. | ALA4430905 | B | Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake at 10 uM incubated for 5 mins by liquid scintillation counting method | Homo sapiens | 1 | ALA4428119 | cell-based format | Scientific Literature | |
4. | ALA4430906 | B | Inhibition of human EAAT3 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake at 10 uM incubated for 5 mins by liquid scintillation counting method | Homo sapiens | 1 | ALA4428119 | cell-based format | Scientific Literature | |
5. | ALA4430907 | B | Inhibition of human EAAT1 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 5 mins by liquid scintillation counting method | Homo sapiens | 37 | ALA4428119 | cell-based format | Scientific Literature | |
6. | ALA4430908 | B | Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 5 mins by liquid scintillation counting method | Homo sapiens | 37 | ALA4428119 | cell-based format | Scientific Literature | |
7. | ALA4430909 | B | Inhibition of human EAAT3 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 5 mins by liquid scintillation counting method | Homo sapiens | 37 | ALA4428119 | cell-based format | Scientific Literature | |
8. | ALA4430910 | B | Selectivity index, ratio of IC50 for human EAAT2 expressed in HEK293 cells to IC50 for human EAAT1 expressed in HEK293 cells | Homo sapiens | 1 | ALA4428119 | cell-based format | Scientific Literature | |
9. | ALA4430911 | B | Selectivity index, ratio of IC50 for human EAAT3 expressed in HEK293 cells to IC50 for human EAAT1 expressed in HEK293 cells | Homo sapiens | 1 | ALA4428119 | cell-based format | Scientific Literature |