# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1037160 | B | Inhibition of ovine COX-1 assessed as inhibition of transformation of AA to PGH2 by EIA | Ovis aries | 27 | single protein format | Scientific Literature | ||
2. | ALA1037161 | B | Inhibition of ovine COX-2 assessed as inhibition of transformation of AA to PGH2 by EIA | Ovis aries | 27 | single protein format | Scientific Literature | ||
3. | ALA1037162 | B | Inhibition of potato LOX-5 assessed as inhibition of hydroperoxide production after 5 mins by EIA | Solanum tuberosum | 27 | assay format | Scientific Literature | ||
4. | ALA1037163 | B | Selectivity ratio of IC50 for ovine COX-1 to IC50 for ovine COX-2 | Ovis aries | 27 | assay format | Scientific Literature | ||
5. | ALA1037164 | F | Antiplatelet activity in rabbit platelets assessed as inhibition of platelet activating factor-induced platelet aggregation | Oryctolagus cuniculus | 27 | cell-based format | Scientific Literature | ||
6. | ALA1037165 | F | Antiplatelet activity in rabbit platelets assessed as inhibition of arachidonic acid-induced platelet aggregation | Oryctolagus cuniculus | 27 | cell-based format | Scientific Literature | ||
7. | ALA1037166 | F | Antiplatelet activity in rabbit platelets assessed as inhibition of adenosin 5'-diphosphate-induced platelet aggregation | Oryctolagus cuniculus | 27 | cell-based format | Scientific Literature | ||
8. | ALA3107267 | F | Antiplatelet activity against New Zealand white rabbit platelets assessed as inhibition of PAF-induced platelet aggregation preincubated at 100 uM for 2 mins before challenge measured after 2 mins by spectrophotometry | Oryctolagus cuniculus | 15 | cell-based format | Scientific Literature | ||
9. | ALA3107269 | F | Antiplatelet activity against New Zealand white rabbit platelets assessed as inhibition of arachidonic acid-induced platelet aggregation preincubated at 100 uM for 2 mins before challenge measured after 2 mins by spectrophotometry | Oryctolagus cuniculus | 16 | cell-based format | Scientific Literature | ||
10. | ALA3107270 | F | Antiplatelet activity against New Zealand white rabbit platelets assessed as inhibition of ADP-induced platelet aggregation preincubated for 2 mins before challenge measured after 2 mins by spectrophotometry | Oryctolagus cuniculus | 10 | cell-based format | Scientific Literature | ||
11. | ALA3107272 | F | Antiplatelet activity against New Zealand white rabbit platelets assessed as inhibition of ADP-induced platelet aggregation preincubated at 100 uM for 2 mins before challenge measured after 2 mins by spectrophotometry | Oryctolagus cuniculus | 15 | cell-based format | Scientific Literature | ||
12. | ALA4022455 | B | Inhibition of Streptococcus pneumoniae sialidase NanB using 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid as substrate after 60 mins by FRET assay | Streptococcus pneumoniae | 13 | assay format | Scientific Literature | ||
13. | ALA4022456 | B | Inhibition of Streptococcus pneumoniae sialidase NanA using 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid as substrate after 60 mins by FRET assay | Streptococcus pneumoniae | 13 | single protein format | Scientific Literature | ||
14. | ALA4022457 | B | Noncompetitive inhibition of Streptococcus pneumoniae sialidase NanA using 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid as substrate after 60 mins by Lineweaver-Burk plot/Dixon plot analysis | Streptococcus pneumoniae | 8 | single protein format | Scientific Literature | ||
15. | ALA4022458 | B | Noncompetitive inhibition of Streptococcus pneumoniae sialidase NanB using 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid as substrate after 60 mins by Lineweaver-Burk plot/Dixon plot analysis | Streptococcus pneumoniae | 5 | assay format | Scientific Literature | ||
16. | ALA4022459 | B | Inhibition of Streptococcus pneumoniae sialidase NanC using 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid as substrate after 60 mins by FRET assay | Streptococcus pneumoniae | 12 | assay format | Scientific Literature | ||
17. | ALA4022460 | B | Noncompetitive inhibition of Streptococcus pneumoniae sialidase NanC using 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid as substrate after 60 mins by Lineweaver-Burk plot/Dixon plot analysis | Streptococcus pneumoniae | 6 | assay format | Scientific Literature |