| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1041718 | B | Inhibition of SCD1 in rat liver microsomes assessed as formation of oleoyl-CoA from 9,10-3H-steroyl-CoA | Rattus norvegicus | 11 | microsome format | Scientific Literature | ||
| 2. | ALA1037262 | A | Metabolic stability in rat hepatocytes assessed as parent remaining at 20 uM | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
| 3. | ALA1072554 | B | Inhibition of SCD1 in rat liver microsomes | Rattus norvegicus | 34 | microsome format | Scientific Literature | ||
| 4. | ALA2320319 | B | Inhibition of delta6 desaturase in Sprague-Dawley rat liver microsome using cis,cis-9,12-octadecadienoic acid substrate at 10 uM | Rattus norvegicus | 30 | microsome format | Scientific Literature | ||
| 5. | ALA2320320 | B | Inhibition of delta5 desaturase in Sprague-Dawley rat liver microsome at 10 uM | Rattus norvegicus | 30 | microsome format | Scientific Literature | ||
| 6. | ALA2321432 | A | Oral bioavailability in Lewis rat at 5 mg/kg | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 7. | ALA2321433 | A | AUC (0 to infinity) in Lewis rat at 5 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 8. | ALA2321434 | A | Cmax in Lewis rat at 5 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 9. | ALA2321435 | A | Tmax in Lewis rat at 5 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 10. | ALA2321440 | A | Clearance in Lewis rat at 3 mg/kg, iv | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 11. | ALA2321441 | A | Volume of distribution at steady state in Lewis rat at 3 mg/kg, iv | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 12. | ALA2321442 | A | AUC (0 to infinity) in Lewis rat at 3 mg/kg, iv | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 13. | ALA2321443 | A | Half life in Lewis rat at 3 mg/kg, iv | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 14. | ALA2321446 | F | In vivo inhibition of SCD1 in Lewis rat liver microsome at 15 mg/kg, ip administered qd for 2 days | Rattus norvegicus | 12 | organism-based format | Scientific Literature | ||
| 15. | ALA2321447 | A | Apparent permeability from basolateral to apical side in human Caco2 cells | Homo sapiens | 50 | cell-based format | Scientific Literature | ||
| 16. | ALA2321448 | A | Metabolic stability in rat liver microsome after 30 mins by LC/MS/MS analysis | Rattus norvegicus | 51 | microsome format | Scientific Literature | ||
| 17. | ALA2321450 | A | Apparent permeability from apical to basolateral side in human Caco2 cells | Homo sapiens | 51 | cell-based format | Scientific Literature | ||
| 18. | ALA2321455 | B | Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrs | Homo sapiens | 56 | cell-based format | Scientific Literature | ||
| 19. | ALA2321456 | B | Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water after 20 hrs by scintillation counting analysis | Mus musculus | 57 | microsome format | Scientific Literature |
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