# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1048885 | Functional | Induction of Wistar rat peritoneal mast cell degradation assessed as concanavalin A-induced histamine release at 0.01 to 10 uM after 15 mins fluorometric assay | Rattus norvegicus | 13 | ALA1156051 | cell-based format | Scientific Literature | |
2. | ALA1048886 | Functional | Induction of C57BL/6 mouse peritoneal mast cell degradation assessed as concanavalin A-induced histamine release at 0.01 to 10 uM after 15 mins fluorometric assay | Mus musculus | 13 | ALA1156051 | cell-based format | Scientific Literature | |
3. | ALA1049709 | Functional | Induction of Wistar rat peritoneal mast cell degradation assessed as concanavalin A-induced histamine release after 15 mins fluorometric assay | Rattus norvegicus | 23 | ALA1156051 | cell-based format | Scientific Literature | |
4. | ALA1049710 | Functional | Induction of C57BL/6 mouse peritoneal mast cell degradation assessed as concanavalin A-induced histamine release after 15 mins fluorometric assay | Mus musculus | 23 | ALA1156051 | cell-based format | Scientific Literature | |
5. | ALA1049711 | Functional | Ratio of lysophosphatidylserine EC50 to compound EC50 for induction of concanavalin A-stimulated Wistar rat peritoneal mast cell degradation associated histamine release | Rattus norvegicus | 1 | ALA1156051 | cell-based format | Scientific Literature | |
6. | ALA1049712 | Functional | Ratio of lysophosphatidylserine EC50 to compound EC50 for induction of concanavalin A-stimulated C57BL/6 mouse peritoneal mast cell degradation associated histamine release | Mus musculus | 1 | ALA1156051 | cell-based format | Scientific Literature | |
7. | ALA1049713 | Functional | Induction of Wistar rat peritoneal mast cell degradation assessed as anti-DNP IgE-induced histamine release at 0.01 to 10 uM after 15 mins fluorometric assay | Rattus norvegicus | 2 | ALA1156051 | cell-based format | Scientific Literature | |
8. | ALA1049714 | Functional | Ratio of compound activity over lysophosphatidylserine activity for induction of anti-DNP IgE-stimulated Wistar rat peritoneal mast cell degradation associated histamine release | Rattus norvegicus | 1 | ALA1156051 | cell-based format | Scientific Literature | |
9. | ALA1049715 | Functional | Increase in plasma histamine level in iv dosed C57BL/6 mouse after 2 mins by EIA | Mus musculus | 3 | ALA1156051 | organism-based format | Scientific Literature | |
10. | ALA1049716 | ADME | Cytotoxicity against concanavalin A-stimulated Wistar rat peritoneal mast cells assessed as LDH release at 50 uM | Rattus norvegicus | 3 | ALA1156051 | cell-based format | Scientific Literature | |
11. | ALA1049717 | Functional | Effect on hypothermic effect in C57BL/6 mouse assessed as reduction in rectal temperature at 1 to 5 ug, iv measured every 5 to 10 mins for 60 mins | Mus musculus | 1 | ALA1156051 | organism-based format | Scientific Literature | |
12. | ALA1038193 | Functional | Effect on hypothermic effect in Wistar rat assessed as reduction in rectal temperature at 20 to 100 ug, iv measured every 5 to 10 mins for 60 mins | Rattus norvegicus | 1 | ALA1156051 | organism-based format | Scientific Literature | |
13. | ALA1038195 | Functional | Ratio of compound activity over lysophosphatidylserine activity for induction of hypothermic effect in Wistar rat | Rattus norvegicus | 1 | ALA1156051 | organism-based format | Scientific Literature | |
14. | ALA1048039 | Functional | Ratio of compound activity over lysophosphatidylserine activity for induction of hypothermic effect in C57BL/6 mouse | Mus musculus | 1 | ALA1156051 | organism-based format | Scientific Literature | |
15. | ALA1048043 | Functional | Activation of mouse GPR34 expressed in CHOK1 cells assessed as inhibition of forskolin-induced cAMP production at 0.01 to 10 uM after 30 mins by EIA | Mus musculus | 2 | ALA1156051 | cell-based format | Scientific Literature | |
16. | ALA1048044 | Functional | Activation of mouse GPR34 expressed in CHOK1 cells assessed as increase in intracellular calcium level by spectrofluorimetry | Mus musculus | 2 | ALA1156051 | cell-based format | Scientific Literature | |
17. | ALA1048045 | Functional | Activation of rat GPR34 expressed in CHOK1 cells assessed as increase in intracellular calcium level by spectrofluorimetry | Rattus norvegicus | 2 | ALA1156051 | cell-based format | Scientific Literature | |
18. | ALA1048046 | Binding | Activation of mouse GPR34 expressed in CHOK1 cells assessed as phosphorylated ERK level at 0.01 to 10 uM by Western blotting | Mus musculus | 2 | ALA1156051 | cell-based format | Scientific Literature | |
19. | ALA1048047 | Binding | Activation of rat GPR34 expressed in CHOK1 cells assessed as phosphorylated ERK level at 0.01 to 10 uM by Western blotting | Rattus norvegicus | 2 | ALA1156051 | cell-based format | Scientific Literature | |
20. | ALA1048048 | Binding | Activation of mouse GPR34 expressed in CHOK1 cells assessed as total ERK level at 0.01 to 10 uM by Western blotting | Mus musculus | 2 | ALA1156051 | cell-based format | Scientific Literature |