# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1049709 | Functional | Induction of Wistar rat peritoneal mast cell degradation assessed as concanavalin A-induced histamine release after 15 mins fluorometric assay | Rattus norvegicus | 23 | ALA1156051 | cell-based format | Scientific Literature | |
2. | ALA1049710 | Functional | Induction of C57BL/6 mouse peritoneal mast cell degradation assessed as concanavalin A-induced histamine release after 15 mins fluorometric assay | Mus musculus | 23 | ALA1156051 | cell-based format | Scientific Literature | |
3. | ALA1049713 | Functional | Induction of Wistar rat peritoneal mast cell degradation assessed as anti-DNP IgE-induced histamine release at 0.01 to 10 uM after 15 mins fluorometric assay | Rattus norvegicus | 2 | ALA1156051 | cell-based format | Scientific Literature | |
4. | ALA1049716 | ADME | Cytotoxicity against concanavalin A-stimulated Wistar rat peritoneal mast cells assessed as LDH release at 50 uM | Rattus norvegicus | 3 | ALA1156051 | cell-based format | Scientific Literature | |
5. | ALA1038192 | Functional | Effect on hypothermic effect in C57BL/6 mouse assessed as reduction in rectal temperature at 25 to 100 ug, iv measured every 5 to 10 mins for 60 mins | Mus musculus | 1 | ALA1156051 | organism-based format | Scientific Literature | |
6. | ALA1038194 | Functional | Effect on hypothermic effect in Wistar rat assessed as reduction in rectal temperature at 20 to 200 ug, iv measured every 5 to 10 mins for 60 mins | Rattus norvegicus | 1 | ALA1156051 | organism-based format | Scientific Literature | |
7. | ALA1048042 | Functional | Effect on hypothermic effect in mast cell-deficient WBB6F1 mouse assessed as reduction in rectal temperature at 10 ug, iv measured every 5 to 10 mins for 60 mins | Mus musculus | 2 | ALA1156051 | organism-based format | Scientific Literature | |
8. | ALA1048043 | Functional | Activation of mouse GPR34 expressed in CHOK1 cells assessed as inhibition of forskolin-induced cAMP production at 0.01 to 10 uM after 30 mins by EIA | Mus musculus | 2 | ALA1156051 | cell-based format | Scientific Literature | |
9. | ALA1048044 | Functional | Activation of mouse GPR34 expressed in CHOK1 cells assessed as increase in intracellular calcium level by spectrofluorimetry | Mus musculus | 2 | ALA1156051 | cell-based format | Scientific Literature | |
10. | ALA1048045 | Functional | Activation of rat GPR34 expressed in CHOK1 cells assessed as increase in intracellular calcium level by spectrofluorimetry | Rattus norvegicus | 2 | ALA1156051 | cell-based format | Scientific Literature | |
11. | ALA1048046 | Binding | Activation of mouse GPR34 expressed in CHOK1 cells assessed as phosphorylated ERK level at 0.01 to 10 uM by Western blotting | Mus musculus | 2 | ALA1156051 | cell-based format | Scientific Literature | |
12. | ALA1048047 | Binding | Activation of rat GPR34 expressed in CHOK1 cells assessed as phosphorylated ERK level at 0.01 to 10 uM by Western blotting | Rattus norvegicus | 2 | ALA1156051 | cell-based format | Scientific Literature | |
13. | ALA1048048 | Binding | Activation of mouse GPR34 expressed in CHOK1 cells assessed as total ERK level at 0.01 to 10 uM by Western blotting | Mus musculus | 2 | ALA1156051 | cell-based format | Scientific Literature | |
14. | ALA1048049 | Binding | Activation of rat GPR34 expressed in CHOK1 cells assessed as total ERK level at 0.01 to 10 uM by Western blotting | Rattus norvegicus | 2 | ALA1156051 | cell-based format | Scientific Literature | |
15. | ALA1048050 | Functional | Inhibition of forskolin-induced cAMP production in CHOK1 cells at 0.01 to 10 uM after 30 mins by EIA | Cricetulus griseus | 2 | ALA1156051 | cell-based format | Scientific Literature | |
16. | ALA1048051 | Functional | Increase in intracellular calcium level in CHOK1 cells by spectrofluorimetry | Cricetulus griseus | 2 | ALA1156051 | cell-based format | Scientific Literature | |
17. | ALA1048052 | Functional | Increase in MAPK level in CHOK1 cells at 0.01 to 10 uM by Western blotting | Cricetulus griseus | 2 | ALA1156051 | cell-based format | Scientific Literature | |
18. | ALA1048887 | Functional | Stimulation of mouse bone marrow-derived mast cell degranulation | Mus musculus | 1 | ALA1156051 | cell-based format | Scientific Literature |