# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1048878 | B | Inhibition of human recombinant ACC 1 expressed in baculovirus expression system by FAS-coupled assay | Homo sapiens | 41 | ALA1156049 | assay format | Scientific Literature | |
2. | ALA1048879 | B | Inhibition of human recombinant ACC 2 expressed in baculovirus expression system by FAS-coupled assay | Homo sapiens | 41 | ALA1156049 | assay format | Scientific Literature | |
3. | ALA1048881 | B | Selectivity ratio of IC50 for human ACC 2 to IC50 for human ACC 1 | Homo sapiens | 3 | ALA1156049 | assay format | Scientific Literature | |
4. | ALA4714232 | B | Inhibition of recombinant human N-terminal His6-tagged ACC1 expressed in baculovirus infected Sf9 insect cells using acetyl-CoA as substrate preincubated for 60 mins followed by substrate addition and measured after 30 mins Rapidfire-Mass spectrometry | Homo sapiens | 15 | ALA4706693 | cell-based format | Scientific Literature | |
5. | ALA4714233 | B | Inhibition of recombinant human N-terminal His6-tagged ACC2 expressed in baculovirus infected Sf9 insect cells using acetyl-CoA as substrate preincubated for 60 mins followed by substrate addition and measured after 30 mins Rapidfire-Mass spectrometry | Homo sapiens | 15 | ALA4706693 | cell-based format | Scientific Literature | |
6. | ALA4714234 | B | Inhibition of recombinant human N-terminal His6-tagged ACC1 expressed in baculovirus infected Sf9 insect cells at 10 uM using acetyl-CoA as substrate preincubated for 60 mins followed by substrate addition and measured after 30 mins Rapidfire-Mass spectrometry relative to control | Homo sapiens | 3 | ALA4706693 | cell-based format | Scientific Literature | |
7. | ALA4714235 | B | Inhibition of recombinant human N-terminal His6-tagged ACC2 expressed in baculovirus infected Sf9 insect cells at 10 uM using acetyl-CoA as substrate preincubated for 60 mins followed by substrate addition and measured after 30 mins Rapidfire-Mass spectrometry relative to control | Homo sapiens | 3 | ALA4706693 | cell-based format | Scientific Literature |