| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1037217 | F | Allosteric modulation of rat NK2 receptor expressed in HEK293 cells assessed as formation of active receptor calcium-triggering conformation at 10 uM in presence of 20nM NKA-Bo by FRET assay | Rattus norvegicus | 30 | cell-based format | Scientific Literature | ||
| 2. | ALA1037218 | F | Allosteric modulation of rat NK2 receptor expressed in HEK293 cells assessed as formation of active receptor calcium-triggering conformation at 50 uM in presence of 20nM NKA-Bo by FRET assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA1037219 | F | Allosteric modulation of rat NK2 receptor expressed in HEK293 cells assessed as formation of active receptor cAMP-producing conformation at 10 uM in presence of 20nM NKA-Bo by FRET assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA1037220 | F | Allosteric modulation of rat NK2 receptor expressed in HEK293 cells assessed as formation of active receptor cAMP-producing conformation at 50 uM in presence of 20nM NKA-Bo by FRET assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA1037221 | F | Allosteric modulation of rat NK2 receptor expressed in HEK293 cells assessed as enhancement of neurokinin A-induced intracellular calcium level at 20 uM by spectrofluorimetry | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
| 6. | ALA1039886 | F | Allosteric modulation of rat NK2 receptor expressed in HEK293 cells assessed as reduction of neurokinin A-induced cAMP production at 10 uM by radioimmunoassay | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
| 7. | ALA1039887 | B | Inhibition of NKA-Bo binding to rat NK2 receptor expressed in HEK293 cells at 10 uM by FRET assay relative to neurokinin A | Rattus norvegicus | 30 | cell-based format | Scientific Literature | ||
| 8. | ALA4309945 | F | Negative allosteric modulation of NK2 receptor (unknown origin) assessed as decrease in agonist-induced cAMP production at 10 uM by cell based FRET assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature |
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