# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1037217 | Functional | Allosteric modulation of rat NK2 receptor expressed in HEK293 cells assessed as formation of active receptor calcium-triggering conformation at 10 uM in presence of 20nM NKA-Bo by FRET assay | Rattus norvegicus | 30 | ALA1156054 | cell-based format | Scientific Literature | |
2. | ALA1037221 | Functional | Allosteric modulation of rat NK2 receptor expressed in HEK293 cells assessed as enhancement of neurokinin A-induced intracellular calcium level at 20 uM by spectrofluorimetry | Rattus norvegicus | 2 | ALA1156054 | cell-based format | Scientific Literature | |
3. | ALA1039886 | Functional | Allosteric modulation of rat NK2 receptor expressed in HEK293 cells assessed as reduction of neurokinin A-induced cAMP production at 10 uM by radioimmunoassay | Rattus norvegicus | 2 | ALA1156054 | cell-based format | Scientific Literature | |
4. | ALA1039887 | Binding | Inhibition of NKA-Bo binding to rat NK2 receptor expressed in HEK293 cells at 10 uM by FRET assay relative to neurokinin A | Rattus norvegicus | 30 | ALA1156054 | cell-based format | Scientific Literature |