| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1040691 | F | NOVARTIS: Inhibition of Plasmodium falciparum 3D7 (drug-susceptible) proliferation in erythrocyte-based infection assay | Plasmodium falciparum | 5,614 | ALA1156829 | organism-based format | Novartis Malaria Screening | |
| 2. | ALA1040692 | F | NOVARTIS: Inhibition of Plasmodium falciparum W2 (drug-resistant) proliferation in erythrocyte-based infection assay | Plasmodium falciparum | 5,614 | ALA1156829 | organism-based format | Novartis Malaria Screening | |
| 3. | ALA1040693 | T | NOVARTIS: Cytotoxicity against human hepatocellular carcinoma cell line (Huh7) | Homo sapiens | 5,614 | ALA1156829 | cell-based format | Novartis Malaria Screening | |
| 4. | ALA1040694 | F | NOVARTIS: Inhibition Frequency Index (IFI) - the number of HTS assays where a compound showed > 50% inhibition/induction, expressed as a percentage of the number of assays in which the compound was tested. | 5,614 | ALA1156829 | assay format | Novartis Malaria Screening | ||
| 5. | ALA1614174 | F | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Bacillus subtilis Sfp phosphopantetheinyl transferase (PPTase). (Class of assay: confirmatory) | Bacillus subtilis | 24,076 | ALA1201862 | assay format | PubChem BioAssays | |
| 6. | ALA1614236 | F | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Influenza NS1 Protein Function. (Class of assay: confirmatory) | Influenza A virus (A/WSN/1933(H1N1)) | 32,268 | ALA1201862 | assay format | PubChem BioAssays | |
| 7. | ALA1614249 | B | PUBCHEM_BIOASSAY: qHTS Assay for Identification of Novel General Anesthetics. In this assay, a GABAergic mimetic model system, apoferritin and a profluorescent 1-aminoanthracene ligand (1-AMA), was used to construct a competitive binding assay for identification of novel general anesthetics (Class of assay: confirmatory) [Related pubchem assays: 2385 (Probe Development Summary for Identification of Novel General Anesthetics), 2323 (Validation apoferritin assay run on SigmaAldrich LOPAC1280 collection)] | Equus caballus | 42,059 | ALA1201862 | single protein format | PubChem BioAssays | |
| 8. | ALA1614250 | F | PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization. (Class of assay: confirmatory) [Related pubchem assays: 596 ] | Homo sapiens | 20,446 | ALA1201862 | assay format | PubChem BioAssays | |
| 9. | ALA1614459 | F | PUBCHEM_BIOASSAY: qHTS Assay for Lipid Storage Modulators in Drosophila S3 Cells. (Class of assay: confirmatory) | Drosophila | 88,408 | ALA1201862 | assay format | PubChem BioAssays | |
| 10. | ALA1614517 | B | PubChem BioAssay. Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput counterscreen to identify inhibitors of TEM-1 metallo-beta-lactamase. (Class of assay: confirmatory) | Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67 | 93 | ALA1201862 | single protein format | PubChem BioAssays | |
| 11. | ALA1614257 | F | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide. (Class of assay: confirmatory) | Homo sapiens | 37,649 | ALA1201862 | assay format | PubChem BioAssays | |
| 12. | ALA1614263 | F | PUBCHEM_BIOASSAY: Quantitative High-Throughput Screen for Regulators of Epigenetic Control. (Class of assay: confirmatory) [Related pubchem assays: 1041, 1039, 890, 1036, 1653, 1035, 1043, 1038, 990, 597, 1042, 1037 ] | 5,529 | ALA1201862 | assay format | PubChem BioAssays | ||
| 13. | ALA1614280 | F | PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of L3MBTL1. (Class of assay: confirmatory) [Related pubchem assays: 485292 (Probe Development Summary for Inhibitors of L3MBTL1)] | Homo sapiens | 13,811 | ALA1201862 | assay format | PubChem BioAssays | |
| 14. | ALA1614342 | F | PUBCHEM_BIOASSAY: qHTS Assay for NPC1 Promoter Activators. (Class of assay: confirmatory) | Homo sapiens | 18,552 | ALA1201862 | assay format | PubChem BioAssays | |
| 15. | ALA1614346 | B | PubChem BioAssay. Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput screening assay to identify inhibitors of IMP-1metallo-beta-lactamase. (Class of assay: confirmatory) | Pseudomonas aeruginosa | 93 | ALA1201862 | single protein format | PubChem BioAssays | |
| 16. | ALA1614405 | F | PUBCHEM_BIOASSAY: Counterscreen for APE1 Inhibitors: Confirmatory Fluorescent Dye Displacement Assay. (Class of assay: confirmatory) [Related pubchem assays: 2565 (Counterscreen for APE1 Inhibitors: qHTS Assay for Inhibitors of Endonuclease IV), 1705 (qHTS Validation Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1)), 2324 (Probe Development Summary of Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1)), 1707 (Counterscreen for APE1 Inhibitors: Fluorescent Dye Displacement Validation Assay), 2517 (qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1)), 2572 (Confirmation qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1)), 1708 (Counterscreen for APE1 Inhibitors: qHTS Validation Assay for Inhibitors of Endonuclease IV)] | 143 | ALA1201862 | assay format | PubChem BioAssays | ||
| 17. | ALA1614410 | F | PUBCHEM_BIOASSAY: qHTS Fluorescence Polarization Assay for Inhibitors of MLL CXXC domain - DNA interaction. (Class of assay: confirmatory) [Related pubchem assays: 2698 (Summary assay.)] | Homo sapiens | 17,175 | ALA1201862 | assay format | PubChem BioAssays | |
| 18. | ALA1614466 | F | PUBCHEM_BIOASSAY: Confirmation qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) [Related pubchem assays: 1705 (qHTS Validation Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1) ), 2324 (Probe Development Summary of Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1)), 1707 (Counterscreen for APE1 Inhibitors: Fluorescent Dye Displacement Validation Assay), 2517 (qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1)), 1708 (Counterscreen for APE1 Inhibitors: qHTS Validation Assay for Inhibitors of Endonuclease IV)] | Homo sapiens | 573 | ALA1201862 | assay format | PubChem BioAssays | |
| 19. | ALA1614474 | F | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Ubiquitin-specific Protease USP2a Using CHOP2 as the Reporter. (Class of assay: confirmatory) [Related pubchem assays: 2281 (Summary of qHTS Assay for Inhibitors of Ubiquitin-specific Protease USP2a), 463106 (LOPAC Validation Assay for Inhibitors of Ubiquitin-specific Protease USP2a)] | Homo sapiens | 1,511 | ALA1201862 | assay format | PubChem BioAssays | |
| 20. | ALA1614531 | F | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Fluorescein Labeled MLL-derived Peptide. (Class of assay: confirmatory) | Homo sapiens | 9,451 | ALA1201862 | assay format | PubChem BioAssays |
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