| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3562077 | Functional | PubChem BioAssay. High Throughput Screening for Foot and Mouth Disease Virus Antivirals. (Class of assay: confirmatory) | 69,295 | ALA1201862 | assay format | PubChem BioAssays | ||
| 2. | ALA1738501 | Functional | PUBCHEM_BIOASSAY: Intein inhibitors as potential Tuberculosis drugs, a cytotoxicity screen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2221, AID2223, AID434968, AID435010, AID449749, AID449750, AID489010] | 77 | ALA1201862 | assay format | PubChem BioAssays | ||
| 3. | ALA1738191 | Binding | PUBCHEM_BIOASSAY: GFP-RecA MOA-DTT Measured in Biochemical System Using Plate Reader - 2047-05_Inhibitor_Dose_DryPowder_Activity. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2223] | Mycobacterium tuberculosis H37Rv | 6 | ALA1201862 | biochemical format | PubChem BioAssays | |
| 4. | ALA1738201 | Binding | PUBCHEM_BIOASSAY: GFP Counter Screen Measured in Biochemical System Using Plate Reader - 2047-03_Inhibitor_Dose_DryPowder_Activity. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2223] | 7 | ALA1201862 | biochemical format | PubChem BioAssays | ||
| 5. | ALA1789905 | Functional | NOVARTIS: Antimalarial liver stage activity measured as a greater than 50% reduction in Plasmodium yoelii schizont area in HepG2-A16-CD81 cells at 10uM compound concentration, determined by immuno-fluorescence. | Plasmodium yoelii | 4,416 | ALA1789904 | organism-based format | Novartis Malaria Screening | |
| 6. | ALA1794349 | Functional | PUBCHEM_BIOASSAY: Fluorescence Cell-Free Homogeneous Secondary Screen to Identify Non-Covalent Inhibitors of RecA-Intein Splicing Activity. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2223, AID489010, AID492950] | 2,123 | ALA1201862 | assay format | PubChem BioAssays | ||
| 7. | ALA1794324 | Functional | PUBCHEM_BIOASSAY: Fluorescence Cell-Free Homogeneous Secondary Screen to Identify Inhibitors of DnaB-Intein Splicing Activity. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2223, AID489010, AID492950] | 2,066 | ALA1201862 | assay format | PubChem BioAssays | ||
| 8. | ALA1794345 | Functional | PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] | Plasmodium falciparum | 170,142 | ALA1201862 | organism-based format | PubChem BioAssays | |
| 9. | ALA1794424 | Functional | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488771] | 30,565 | ALA1201862 | assay format | PubChem BioAssays | ||
| 10. | ALA1794426 | Functional | PUBCHEM_BIOASSAY: Fluorescence Cell-Free Homogeneous Dose Retest to Identify Inhibitors of RecA-Intein Splicing Activity. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2097, AID2223, AID489010, AID492950] | 2,118 | ALA1201862 | assay format | PubChem BioAssays | ||
| 11. | ALA1794483 | Functional | PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] | 114,923 | ALA1201862 | assay format | PubChem BioAssays | ||
| 12. | ALA1794512 | Functional | PUBCHEM_BIOASSAY: qHTS for Inhibitors of Cell Surface uPA Generation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493178] | 12,416 | ALA1201862 | assay format | PubChem BioAssays | ||
| 13. | ALA1794553 | Functional | PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588855, AID588860] | Homo sapiens | 58,172 | ALA1201862 | cell-based format | PubChem BioAssays | |
| 14. | ALA1794580 | Functional | PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] | Plasmodium falciparum | 130,890 | ALA1201862 | organism-based format | PubChem BioAssays | |
| 15. | ALA1794584 | Functional | PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860] | 63,980 | ALA1201862 | assay format | PubChem BioAssays | ||
| 16. | ALA1040691 | Functional | NOVARTIS: Inhibition of Plasmodium falciparum 3D7 (drug-susceptible) proliferation in erythrocyte-based infection assay | Plasmodium falciparum | 5,614 | ALA1156829 | organism-based format | Novartis Malaria Screening | |
| 17. | ALA1040692 | Functional | NOVARTIS: Inhibition of Plasmodium falciparum W2 (drug-resistant) proliferation in erythrocyte-based infection assay | Plasmodium falciparum | 5,614 | ALA1156829 | organism-based format | Novartis Malaria Screening | |
| 18. | ALA1040693 | Toxicity | NOVARTIS: Cytotoxicity against human hepatocellular carcinoma cell line (Huh7) | Homo sapiens | 5,614 | ALA1156829 | cell-based format | Novartis Malaria Screening | |
| 19. | ALA1040694 | Functional | NOVARTIS: Inhibition Frequency Index (IFI) - the number of HTS assays where a compound showed > 50% inhibition/induction, expressed as a percentage of the number of assays in which the compound was tested. | 5,614 | ALA1156829 | assay format | Novartis Malaria Screening | ||
| 20. | ALA1738369 | Functional | PUBCHEM_BIOASSAY: Dose response confirmation of uHTS chemical inhibitors of T-cell specific antigen receptor-induced NF-kB activation in a Jurkat cell line using a luminescence assay. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID435003, AID435012, AID465] | 693 | ALA1201862 | cell-based format | PubChem BioAssays |
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