| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1040691 | F | NOVARTIS: Inhibition of Plasmodium falciparum 3D7 (drug-susceptible) proliferation in erythrocyte-based infection assay | Plasmodium falciparum | 5,614 | organism-based format | Novartis Malaria Screening | ||
| 2. | ALA1040692 | F | NOVARTIS: Inhibition of Plasmodium falciparum W2 (drug-resistant) proliferation in erythrocyte-based infection assay | Plasmodium falciparum | 5,614 | organism-based format | Novartis Malaria Screening | ||
| 3. | ALA1040693 | T | NOVARTIS: Cytotoxicity against human hepatocellular carcinoma cell line (Huh7) | Homo sapiens | 5,614 | cell-based format | Novartis Malaria Screening | ||
| 4. | ALA1040694 | F | NOVARTIS: Inhibition Frequency Index (IFI) - the number of HTS assays where a compound showed > 50% inhibition/induction, expressed as a percentage of the number of assays in which the compound was tested. | 5,614 | assay format | Novartis Malaria Screening | |||
| 5. | ALA1614263 | F | PUBCHEM_BIOASSAY: Quantitative High-Throughput Screen for Regulators of Epigenetic Control. (Class of assay: confirmatory) [Related pubchem assays: 1041, 1039, 890, 1036, 1653, 1035, 1043, 1038, 990, 597, 1042, 1037 ] | 5,529 | assay format | PubChem BioAssays | |||
| 6. | ALA1614414 | F | PUBCHEM_BIOASSAY: qHTS Assay for Small Molecule Inhibitors of Mitochondrial Division or Activators of Mitochondrial Fusion. (Class of assay: confirmatory) | Saccharomyces cerevisiae | 8,343 | organism-based format | PubChem BioAssays | ||
| 7. | ALA1614531 | F | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Fluorescein Labeled MLL-derived Peptide. (Class of assay: confirmatory) | Homo sapiens | 9,451 | assay format | PubChem BioAssays | ||
| 8. | ALA1613970 | F | PUBCHEM_BIOASSAY: qHTS Assay for Compounds that Induce Erasure of Genomic Imprints. (Class of assay: confirmatory) | 5,084 | assay format | PubChem BioAssays | |||
| 9. | ALA1614087 | F | PUBCHEM_BIOASSAY: qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) | Mus musculus | 51,950 | assay format | PubChem BioAssays | ||
| 10. | ALA1614364 | B | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Tyrosyl-DNA Phosphodiesterase (TDP1). (Class of assay: confirmatory) | Homo sapiens | 11,958 | single protein format | PubChem BioAssays | ||
| 11. | ALA1614421 | B | PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding. (Class of assay: confirmatory) [Related pubchem assays: 596 ] | Homo sapiens | 49,165 | single protein format | PubChem BioAssays | ||
| 12. | ALA1614502 | F | PUBCHEM_BIOASSAY: Counterscreen qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization. This assay monitors tau fibrillation by fluorescence polarization (FP) of Alexa 594-labeled K18 P301L, which does not fibrillize readily but incorporates into growing filaments of unlabeled tau. (Class of assay: confirmatory) [Related pubchem assays: 596 ] | 23,781 | assay format | PubChem BioAssays | |||
| 13. | ALA1614019 | F | PUBCHEM_BIOASSAY: qHTS Assay for Lipid Storage Modulators. (Class of assay: confirmatory) | Drosophila | 2,097 | assay format | PubChem BioAssays | ||
| 14. | ALA1738091 | F | PUBCHEM_BIOASSAY: HTS Assay for Allosteric Agonists of the Human D1 Dopamine Receptor: Primary Screen for Potentiators. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488989, AID488993, AID488995] | Homo sapiens | 305 | assay format | PubChem BioAssays | ||
| 15. | ALA1738675 | F | PUBCHEM_BIOASSAY: Validation screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493125, AID504467] | Homo sapiens | 366 | assay format | PubChem BioAssays | ||
| 16. | ALA1738442 | F | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] | Homo sapiens | 90,358 | assay format | PubChem BioAssays | ||
| 17. | ALA1738565 | F | PUBCHEM_BIOASSAY: HTS Assay for Allosteric Agonists of the Human D1 Dopamine Receptor: Primary Screen for Antagonists. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488989, AID488993, AID488995] | Homo sapiens | 238 | assay format | PubChem BioAssays | ||
| 18. | ALA1738606 | F | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of GCN5L2. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504398] | Homo sapiens | 13,828 | assay format | PubChem BioAssays | ||
| 19. | ALA1738610 | F | PUBCHEM_BIOASSAY: qHTS Validation Assay for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] | Homo sapiens | 592 | assay format | PubChem BioAssays | ||
| 20. | ALA1613775 | F | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488771, AID488772] | Rattus norvegicus | 234 | assay format | PubChem BioAssays |
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