# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA730079 | F | ST_JUDE: Plasmodium falciparum 3D7 EC50 (uM) as measured by SYBR green dye | Plasmodium falciparum | 1,524 | organism-based format | St Jude Malaria Screening | ||
2. | ALA730080 | F | ST_JUDE: Plasmodium falciparum K1 EC50 (uM) as measured by SYBR green dye | Plasmodium falciparum | 1,524 | organism-based format | St Jude Malaria Screening | ||
3. | ALA4729807 | B | Inhibition of recombinant human wild-type N-terminal His-tagged PDIA1 expressed in Escherichia coli strain BL21(DE3) at 40 uM using bovine insulin as substrate preincubated for 1 hr followed by substrate addition relative to control | Homo sapiens | 2 | assay format | Scientific Literature | ||
4. | ALA4729808 | F | Cytotoxicity against human U-87 MG cells assessed as growth inhibition at 30 uM measured after 72 hrs by MTT assay relative to control | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
5. | ALA4729809 | F | Cytotoxicity against human MIA PaCa-2 cells assessed as growth inhibition at 30 uM measured after 72 hrs by MTT assay relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
6. | ALA4729810 | B | Inhibition of recombinant human wild-type N-terminal His-tagged PDIA1 expressed in Escherichia coli strain BL21(DE3) using bovine insulin as substrate preincubated for 1 hr followed by substrate addition | Homo sapiens | 108 | assay format | Scientific Literature | ||
7. | ALA4729811 | B | Inhibition of recombinant human wild-type N-terminal His-tagged PDIA1 H256A mutant expressed in Escherichia coli strain BL21(DE3) using bovine insulin as substrate preincubated for 1 hr followed by substrate addition | Homo sapiens | 2 | assay format | Scientific Literature | ||
8. | ALA4729812 | A | Inhibition of PDIA2 (unknown origin) at 40 uM using bovine insulin as substrate preincubated for 1 hr followed by substrate addition | Homo sapiens | 2 | single protein format | Scientific Literature | ||
9. | ALA4729813 | A | Inhibition of PDIA3 (unknown origin) at 40 uM using bovine insulin as substrate preincubated for 1 hr followed by substrate addition | Homo sapiens | 2 | single protein format | Scientific Literature | ||
10. | ALA4729814 | F | Cytotoxicity against human U-87 MG cells assessed as growth inhibition measured after 72 hrs by MTT assay | Homo sapiens | 106 | cell-based format | Scientific Literature | ||
11. | ALA4729815 | B | Binding affinity to recombinant human wild-type N-terminal His-tagged PDIA1 expressed in Escherichia coli strain BL21(DE3) assessed as change in melting temperature at 100 uM by ROX dye based thermal shift assay | Homo sapiens | 4 | assay format | Scientific Literature | ||
12. | ALA4729821 | B | Irreversible inhibition of recombinant human wild-type N-terminal His-tagged PDIA1 expressed in Escherichia coli strain BL21(DE3) at 50 uM using bovine insulin as substrate preincubated for 3 hrs followed by 100-fold dilution substrate addition further incubated for 1 hr and subsequent substrate addition | Homo sapiens | 2 | assay format | Scientific Literature | ||
13. | ALA4729822 | B | Irreversible inhibition of recombinant human wild-type N-terminal His-tagged PDIA1 expressed in Escherichia coli strain BL21(DE3) at 400 uM using bovine insulin as substrate preincubated for 30 mins followed by 100-fold dilution substrate addition further incubated for 1 hr and subsequent substrate addition | Homo sapiens | 3 | assay format | Scientific Literature | ||
14. | ALA4729823 | B | Displacement of ANS from recombinant human wild-type N-terminal His-tagged PDIA1 expressed in Escherichia coli strain BL21(DE3) at 100 uM measured after 1 hr by fluorescence assay | Homo sapiens | 3 | assay format | Scientific Literature | ||
15. | ALA4729824 | B | Inhibition of recombinant human wild-type N-terminal His-tagged PDIA1 expressed in Escherichia coli strain BL21(DE3) at 10 uM using bovine insulin as substrate preincubated for 1 hr followed by substrate addition in presence of N-acetyl cysteine | Homo sapiens | 4 | assay format | Scientific Literature | ||
16. | ALA4729825 | B | Inhibition of recombinant human wild-type N-terminal His-tagged PDIA1 expressed in Escherichia coli strain BL21(DE3) at 10 uM using bovine insulin as substrate preincubated for 1 hr followed by substrate addition in presence of glutathione | Homo sapiens | 6 | assay format | Scientific Literature | ||
17. | ALA4729826 | B | Inhibition of recombinant human wild-type N-terminal His-tagged PDIA1 expressed in Escherichia coli strain BL21(DE3) at 10 uM using bovine insulin as substrate preincubated for 1 hr followed by substrate and N-acetyl cysteine addition | Homo sapiens | 2 | assay format | Scientific Literature | ||
18. | ALA4729831 | F | Inhibition of colony formation in BSO-treated human U-87 MG cells at 0.3 to 10 uM measured after 10 to 14 days by crystal violet staining based assay | Homo sapiens | 1 | cell-based format | Scientific Literature |