# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA615967 | Binding | In vitro ability to inhibit [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cortical membranes | 16 | ALA1132392 | cell membrane format | Scientific Literature | ||
2. | ALA630197 | Physicochemical | Partition coefficient in octanol-buffer at a pH 7.4 | 8 | ALA1124010 | small-molecule physicochemical format | Scientific Literature | ||
3. | ALA633535 | Physicochemical | Ionization constant in presence of nitrogen | 8 | ALA1124010 | small-molecule physicochemical format | Scientific Literature | ||
4. | ALA634057 | Physicochemical | Ionization constant in presence of hydroxyl | 8 | ALA1124010 | small-molecule physicochemical format | Scientific Literature | ||
5. | ALA663103 | Binding | Potency to displace the specific in vitro binding of [3H]N-0437 to calf striatal membrane | Bos taurus | 7 | ALA1124010 | assay format | Scientific Literature | |
6. | ALA669149 | Binding | In vitro ability to inhibit [3H]raclopride binding to cloned human D2A receptors expressed in mouse fibroblast (LtK-) cells | 15 | ALA1132392 | cell-based format | Scientific Literature | ||
7. | ALA675835 | Binding | In vitro affinity to dopamine receptor using [3H]HPD as radioligand in rat striatal membranes | 3 | ALA1124290 | cell membrane format | Scientific Literature | ||
8. | ALA675836 | Binding | In vitro affinity to dopamine receptor using [3H]NPAD as radioligand in rat striatal membranes | 3 | ALA1124290 | cell membrane format | Scientific Literature | ||
9. | ALA780781 | Functional | Dose (ip) giving half-maximal reversal of the gamma-butyrolactone-induced increase in DOPA formation of rat striatum | Rattus norvegicus | 3 | ALA1124290 | organism-based format | Scientific Literature | |
10. | ALA776430 | Functional | Dose required for inhibition of locomotor activity in mice (sc) | Rattus norvegicus | 3 | ALA1124290 | organism-based format | Scientific Literature | |
11. | ALA776433 | Functional | Dose required for reversal of reserpine-induced depression in mice (sc) | Rattus norvegicus | 3 | ALA1124290 | organism-based format | Scientific Literature | |
12. | ALA770866 | Binding | Potency to displace the specific in vitro binding of [3H]DP-5,6-ADTN to rat striatal membrane | 7 | ALA1124010 | assay format | Scientific Literature | ||
13. | ALA851313 | Functional | Ratio of ED50 values for the inhibition of locomotor activity to reversal of reserpine-induced depression | 3 | ALA1124290 | assay format | Scientific Literature |
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