# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2094261 | F | MMV: Screen against Mtb, single point, non replicating, at 25uM | Mycobacterium tuberculosis | 399 | organism-based format | MMV Malaria Box | ||
2. | ALA2094262 | F | MMV: Screen against Mtb, single point, replicating, at 25uM | Mycobacterium tuberculosis | 399 | organism-based format | MMV Malaria Box | ||
3. | ALA2094263 | F | MMV: CRC and MIC90 against Mtb (non replicating) | Mycobacterium tuberculosis | 55 | organism-based format | MMV Malaria Box | ||
4. | ALA2094264 | F | MMV: CRC and MIC90 against Mtb (replicating) | Mycobacterium tuberculosis | 56 | organism-based format | MMV Malaria Box | ||
5. | ALA2094265 | T | MMV: Cytotoxicity CRC and LD50 against HepG2 | Homo sapiens | 57 | cell-based format | MMV Malaria Box | ||
6. | ALA2028070 | F | MMV: Inhibition of Plasmodium falciparum 3D7 at 5uM compound concentration. | Plasmodium falciparum | 315 | organism-based format | MMV Malaria Box | ||
7. | ALA2028071 | F | MMV: Inhibition of Plasmodium falciparum 3D7 (EC50). | Plasmodium falciparum | 317 | organism-based format | MMV Malaria Box | ||
8. | ALA2028072 | F | MMV: Inhibition of Plasmodium falciparum K1 (EC50). | Plasmodium falciparum | 171 | organism-based format | MMV Malaria Box | ||
9. | ALA2028073 | F | MMV: Inhibition of Trypanosoma cruzi (Tulahuen C4 LacZ) (Chagas in vitro). | Trypanosoma cruzi | 400 | organism-based format | MMV Malaria Box | ||
10. | ALA2028074 | F | MMV: Inhibition of Trypanosoma brucei brucei (Squib 427) (HAT in vitro). | Trypanosoma brucei brucei | 400 | organism-based format | MMV Malaria Box | ||
11. | ALA2028075 | F | MMV: Inhibition of Trypanosoma brucei rhodesiense (STIB 900) (HAT in vitro). | Trypanosoma brucei rhodesiense | 400 | organism-based format | MMV Malaria Box | ||
12. | ALA2028076 | F | MMV: Inhibition of Leishmania infantum (MHOM/MA/BE/67) in vitro. | Leishmania infantum | 400 | organism-based format | MMV Malaria Box | ||
13. | ALA2028077 | T | MMV: Cytotoxicity against human fibroblasts (MRC-5) cells. | Homo sapiens | 400 | cell-based format | MMV Malaria Box | ||
14. | ALA730079 | F | ST_JUDE: Plasmodium falciparum 3D7 EC50 (uM) as measured by SYBR green dye | Plasmodium falciparum | 1,524 | organism-based format | St Jude Malaria Screening | ||
15. | ALA730080 | F | ST_JUDE: Plasmodium falciparum K1 EC50 (uM) as measured by SYBR green dye | Plasmodium falciparum | 1,524 | organism-based format | St Jude Malaria Screening | ||
16. | ALA2363023 | F | MMV: Toxicity @ 2.5 uM to newly transformed Schistosoma mansoni somules after 24 h on a scale of 0 (none) - 4 (most) as judged visually: includes short descriptors of effects (PMID:19597541). Caffrey group UCSF. | Schistosoma mansoni | 400 | organism-based format | MMV Malaria Box | ||
17. | ALA2363024 | F | MMV: Toxicity @ 2.5 uM to newly transformed Schistosoma mansoni somules after 48 h on a scale of 0 (none) - 4 (most) as judged visually: includes short descriptors of effects (PMID:19597541). Caffrey group UCSF. | Schistosoma mansoni | 400 | organism-based format | MMV Malaria Box | ||
18. | ALA2363025 | F | MMV: Toxicity @ 2.5 uM to newly transformed Schistosoma mansoni somules after 72 h on a scale of 0 (none) - 4 (most) as judged visually: includes short descriptors of effects (PMID:19597541). Caffrey group UCSF. | Schistosoma mansoni | 400 | organism-based format | MMV Malaria Box | ||
19. | ALA2363026 | F | MMV: Toxicity @ 5 uM to 4-5 Schistosoma mansoni adult males after 24 h on a scale of 0 (none) - 4 (most). Includes short descriptors of effects as judged visually (PMID:19597541). Only those Malaria box 'drug-like' cpds yielding the most severe phenotypes vs. somules were tested. Caffrey group UCSF. | Schistosoma mansoni | 41 | organism-based format | MMV Malaria Box | ||
20. | ALA2363027 | F | MMV: Toxicity @ 5 uM to 4-5 Schistosoma mansoni adult males after 48 h on a scale of 0 (none) - 4 (most). Includes short descriptors of effects as judged visually (PMID:19597541). Only those Malaria box 'drug-like' cpds yielding the most severe phenotypes vs. somules were tested. Caffrey group UCSF. | Schistosoma mansoni | 41 | organism-based format | MMV Malaria Box |