# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1071884 | B | Inhibition of Scd1 in mouse liver microsomes assessed as conversion of [14C]stearate to [14C]oleate pretreated for 10 mins measured after 60 mins | Mus musculus | 20 | microsome format | Scientific Literature | ||
2. | ALA1071886 | B | Inhibition of Scd1 in human HEK293A cell microsomes assessed as conversion of [14C]stearate to [14C]oleate pretreated for 10 mins measured after 60 mins | Homo sapiens | 20 | microsome format | Scientific Literature | ||
3. | ALA2320319 | B | Inhibition of delta6 desaturase in Sprague-Dawley rat liver microsome using cis,cis-9,12-octadecadienoic acid substrate at 10 uM | Rattus norvegicus | 30 | microsome format | Scientific Literature | ||
4. | ALA2320320 | B | Inhibition of delta5 desaturase in Sprague-Dawley rat liver microsome at 10 uM | Rattus norvegicus | 30 | microsome format | Scientific Literature | ||
5. | ALA2321447 | A | Apparent permeability from basolateral to apical side in human Caco2 cells | Homo sapiens | 50 | cell-based format | Scientific Literature | ||
6. | ALA2321448 | A | Metabolic stability in rat liver microsome after 30 mins by LC/MS/MS analysis | Rattus norvegicus | 51 | microsome format | Scientific Literature | ||
7. | ALA2321450 | A | Apparent permeability from apical to basolateral side in human Caco2 cells | Homo sapiens | 51 | cell-based format | Scientific Literature | ||
8. | ALA2321455 | B | Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrs | Homo sapiens | 56 | cell-based format | Scientific Literature | ||
9. | ALA2321456 | B | Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water after 20 hrs by scintillation counting analysis | Mus musculus | 57 | microsome format | Scientific Literature | ||
10. | ALA4016018 | B | Inhibition of human full length N-terminal His-tagged dCTPase expressed in Escherichia coli BL21(DE3) at 10 uM using dCTP as substrate by HTS-based malachite green assay | Homo sapiens | 1 | assay format | Scientific Literature | ||
11. | ALA4016019 | B | Inhibition of human full length N-terminal His-tagged dCTPase expressed in Escherichia coli BL21(DE3) using dCTP as substrate by HTS-based malachite green assay | Homo sapiens | 27 | assay format | Scientific Literature |