# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA616832 | Binding | Compound was tested for binding affinity towards 5-HT1C (5-HT1C) receptor from frontal cortical regions of male Sprague-Dawley rat homogenates, using [3H]mesulergine as radioligand | Rattus norvegicus | 1 | ALA1125379 | assay format | Scientific Literature | |
2. | ALA616834 | Binding | Binding affinity towards 5-hydroxytryptamine 1C receptor from frontal cortical regions of male Sprague-Dawley rat homogenates, using [3H]mesulergine as radioligand | Rattus norvegicus | 28 | ALA1125379 | assay format | Scientific Literature | |
3. | ALA617438 | Binding | Binding affinity towards 5-hydroxytryptamine 2 receptor from frontal cortical regions of male Sprague-Dawley rat homogenates, using [3H]ketanserin as radioligand | 27 | ALA1125379 | assay format | Scientific Literature | ||
4. | ALA858114 | Binding | Affinity against 5-hydroxytryptamine 2B receptor in the isolated rat stomach fundus | 19 | ALA1121754 | tissue-based format | Scientific Literature | ||
5. | ALA619177 | Binding | Affinity against 5-hydroxytryptamine receptors in rat fundus model | 44 | ALA1121407 | assay format | Scientific Literature | ||
6. | ALA631963 | Functional | Log value of hallucinogenic activity was determined | Homo sapiens | 63 | ALA1125153 | organism-based format | Scientific Literature | |
7. | ALA633218 | Physicochemical | Partition coefficient (logP) | 19 | ALA1121754 | small-molecule physicochemical format | Scientific Literature | ||
8. | ALA696016 | Functional | Hallucinogenic activity i.e; ratio of effective dose of mescaline to the effective dose in human | Homo sapiens | 63 | ALA1125153 | organism-based format | Scientific Literature | |
9. | ALA878435 | Functional | Human hallucinogenic activity relative to mescaline | Homo sapiens | 15 | ALA1121754 | organism-based format | Scientific Literature | |
10. | ALA700102 | Functional | Compound tested for hallucinogenic activity in humans was reported; Value reported in (A)= Mescaline units | Homo sapiens | 91 | ALA1131120 | organism-based format | Scientific Literature | |
11. | ALA773948 | Functional | Hyperthermic potency in rabbit relative to DOM | Oryctolagus cuniculus | 18 | ALA1121754 | organism-based format | Scientific Literature | |
12. | ALA792065 | Functional | Compound was tested for hallucinogenic activity in rats at 0.32dose (mg/kg); Number of rats selecting the LSD lever/ number of rats responding (0/8) | Rattus norvegicus | 1 | ALA1123242 | organism-based format | Scientific Literature | |
13. | ALA792066 | Functional | Compound was tested for hallucinogenic activity in rats at 0.63 dose(mg/kg); Number of rats selecting the LSD lever/ number of rats responding (2/8) | Rattus norvegicus | 2 | ALA1123242 | organism-based format | Scientific Literature | |
14. | ALA797028 | Functional | Compound was tested for hallucinogenic activity in rats at 1.29 dose(mg/kg); Number of rats selecting the LSD lever/ number of rats responding (5/8) | Rattus norvegicus | 1 | ALA1123242 | organism-based format | Scientific Literature | |
15. | ALA792848 | Functional | Compound was tested for hallucinogenic activity in rats at 1.72 dose(mg/kg); Number of rats selecting the LSD lever/ number of rats responding (7/8) | Rattus norvegicus | 1 | ALA1123242 | organism-based format | Scientific Literature | |
16. | ALA784676 | Functional | Compound was tested for hallucinogenic activity in rats at 0.32(mg/kg) | Rattus norvegicus | 1 | ALA1123242 | organism-based format | Scientific Literature | |
17. | ALA785266 | Functional | Compound was tested for hallucinogenic activity in rats at the dose 0 (mg/kg) | Rattus norvegicus | 1 | ALA1123242 | organism-based format | Scientific Literature | |
18. | ALA781226 | Functional | Effective dose for drug discrimination assay in rats using (+)-Amphitamine as training drug; NS = No substitution | Rattus norvegicus | 4 | ALA1131486 | organism-based format | Scientific Literature | |
19. | ALA782002 | Functional | Effective dose in rats trained on 1 mg/kg DOM. | Rattus norvegicus | 16 | ALA1125153 | organism-based format | Scientific Literature | |
20. | ALA779591 | Functional | Compound was tested for its ability to inhibit [3H]dopamine uptake in rat synaptosomes | Rattus norvegicus | 7 | ALA1131486 | organism-based format | Scientific Literature |