# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1074018 | B | Displacement of [125I]PYY from human recombinant Y5 receptor | Homo sapiens | 26 | ALA1152582 | single protein format | Scientific Literature | |
2. | ALA1074019 | A | Clearance in rat hepatocytes | Rattus norvegicus | 26 | ALA1152582 | cell-based format | Scientific Literature | |
3. | ALA1074020 | P | Lipophilicity, log D at pH 7.4 | 26 | ALA1152582 | small-molecule physicochemical format | Scientific Literature | ||
4. | ALA1074021 | A | Plasma concentration in rat at 10 mg/kg, po after 2 hrs | Rattus norvegicus | 26 | ALA1152582 | organism-based format | Scientific Literature | |
5. | ALA1074022 | A | Drug level in rat brain at 10 mg/kg, po after 2 hrs | Rattus norvegicus | 26 | ALA1152582 | organism-based format | Scientific Literature | |
6. | ALA1074023 | A | Drug level in rat CSF at 10 mg/kg, po after 2 hrs | Rattus norvegicus | 26 | ALA1152582 | organism-based format | Scientific Literature | |
7. | ALA1074026 | A | Ratio of drug level in CSF to plasma in rat at 10 mg/kg, po after 2 hrs | Rattus norvegicus | 5 | ALA1152582 | organism-based format | Scientific Literature | |
8. | ALA1074027 | F | Inhibition of [D-Trp34]NPY-induced food intake in Sprague-Dawley rat assessed as minimum effective dose treated po 2 hrs before [D-Trp34]NPY challenge | Rattus norvegicus | 6 | ALA1152582 | organism-based format | Scientific Literature | |
9. | ALA1074028 | B | Inhibition of rat Y5 receptor | Rattus norvegicus | 6 | ALA1152582 | single protein format | Scientific Literature | |
10. | ALA1065420 | A | Ratio of permeability from basolateral to apical side to apical to basolateral side in pig LLC-PK1 cells expressing human MDR1 after 3 hrs | Sus scrofa | 6 | ALA1152582 | cell-based format | Scientific Literature | |
11. | ALA1065421 | A | Ratio of permeability from basolateral to apical side to apical to basolateral side in pig LLC-PK1 cells expressing mouse MDR1a after 3 hrs | Sus scrofa | 6 | ALA1152582 | cell-based format | Scientific Literature |