| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1041633 | F | Antiviral activity against HIV1 NL4-3 infected in human HeLa cells expressing CD4/CCR5-LTR-beta-gal genes assessed as blockade of viral infection by X-gal staining based MAGI method | Human immunodeficiency virus 1 | 3 | organism-based format | Scientific Literature | ||
| 2. | ALA1041634 | A | Stability in mouse serum assessed as compound degradation by LC-MS analysis | Mus musculus | 3 | cell-free format | Scientific Literature | ||
| 3. | ALA3391026 | B | Binding affinity to HIV1 His-tagged N-terminal heptad repeat of envelope glycoprotein gp41 assessed as recovery of N36-drug complex at 10 uM after 2 hrs by LC-MS analysis | Human immunodeficiency virus 1 | 19 | assay format | Scientific Literature | ||
| 4. | ALA3391088 | B | Binding affinity to HIV1 His-tagged N-terminal heptad repeat of envelope glycoprotein gp41 assessed as recovery of N36-drug complex at 6 uM after 2 hrs by LC-MS analysis | Human immunodeficiency virus 1 | 19 | assay format | Scientific Literature | ||
| 5. | ALA3391089 | B | Binding affinity to HIV1 His-tagged N-terminal heptad repeat of envelope glycoprotein gp41 assessed as recovery of N36-drug complex at 1 uM after 2 hrs by LC-MS analysis | Human immunodeficiency virus 1 | 19 | assay format | Scientific Literature | ||
| 6. | ALA3391090 | B | Binding affinity to HIV1 His-tagged N-terminal heptad repeat of envelope glycoprotein gp41 assessed as recovery of N36-drug complex at 0.6 uM after 2 hrs by LC-MS analysis | Human immunodeficiency virus 1 | 19 | assay format | Scientific Literature | ||
| 7. | ALA3391091 | F | Antiviral activity against HIV1 NL4-3 harboring gp41 D36G mutant infected in human HeLa cells expressing CD4-LTR-beta-gal assessed as inhibition of viral replication after 48 hrs by MAGI assay | Human immunodeficiency virus 1 | 74 | organism-based format | Scientific Literature | ||
| 8. | ALA3391092 | B | Thermal stability of HIV1 envelope glycoprotein gp41 His-tagged N-terminal heptad repeat N36-drug complex assessed as thermal unfolding transition state by measuring molar ellipticity at 4 to 90 degC by circular dichroic spectra analysis | Human immunodeficiency virus 1 | 37 | assay format | Scientific Literature | ||
| 9. | ALA3391095 | B | Binding affinity to HIV1 His-tagged N-terminal heptad repeat of envelope glycoprotein gp41 assessed as recovery of N36 V38A mutant-drug complex after 2 hrs by LC-MS analysis | Human immunodeficiency virus 1 | 6 | assay format | Scientific Literature | ||
| 10. | ALA3391096 | B | Binding affinity to HIV1 His-tagged N-terminal heptad repeat of envelope glycoprotein gp41 assessed as recovery of N36 N43D mutant-drug complex after 2 hrs by LC-MS analysis | Human immunodeficiency virus 1 | 6 | assay format | Scientific Literature | ||
| 11. | ALA3391097 | B | Thermal stability of HIV1 envelope glycoprotein gp41 His-tagged N-terminal heptad repeat N36 V38A mutant-drug complex assessed as thermal unfolding transition state by measuring molar ellipticity at 4 to 90 degC by circular dichroic spectra analysis | Human immunodeficiency virus 1 | 6 | assay format | Scientific Literature | ||
| 12. | ALA3391098 | B | Thermal stability of HIV1 envelope glycoprotein gp41 His-tagged N-terminal heptad repeat N36 N43D mutant-drug complex assessed as thermal unfolding transition state by measuring molar ellipticity at 4 to 90 degC by circular dichroic spectra analysis | Human immunodeficiency virus 1 | 6 | assay format | Scientific Literature | ||
| 13. | ALA3391103 | B | Binding affinity to HIV1 His-tagged N-terminal heptad repeat of envelope glycoprotein gp41 assessed as recovery of N36-drug complex after 2 hrs by LC-MS analysis | Human immunodeficiency virus 1 | 19 | assay format | Scientific Literature |
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