# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1066768 | F | Antitrypanosomal activity against Trypanosoma brucei rhodesiense | Trypanosoma brucei rhodesiense | 27 | organism-based format | Scientific Literature | ||
2. | ALA1066769 | F | Antitrypanosomal activity against Trypanosoma cruzi | Trypanosoma cruzi | 27 | organism-based format | Scientific Literature | ||
3. | ALA1067383 | F | Antileishmanial activity against Leishmania donovani axenic amastigotes | Leishmania donovani | 27 | organism-based format | Scientific Literature | ||
4. | ALA1067384 | F | Antimalarial activity against chloroquine and pyrimethamine-resistant Plasmodium falciparum K1 by [3H]hypoxanthine incorporation assay | Plasmodium falciparum | 27 | organism-based format | Scientific Literature | ||
5. | ALA1067385 | T | Toxicity against rat L6 cells | Rattus norvegicus | 31 | cell-based format | Scientific Literature | ||
6. | ALA1067386 | T | Selectivity index, ratio of IC50 for rat L6 cells to IC50 for chloroquine and pyrimethamine-resistant Plasmodium falciparum K1 | 24 | cell-based format | Scientific Literature | |||
7. | ALA4825139 | B | Inhibition of human GluN1-1a/NR2A receptor expressed in transgenic mouse fibroblast cells assessed as inhibition of L-glutamate-induced excitotoxicity at 50 uM by measuring LDH activity by cell based assay | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
8. | ALA4825141 | B | Inhibition of human GluN1-1a/NR2B receptor expressed in transgenic mouse fibroblast cells assessed as inhibition of L-glutamate-induced excitotoxicity at 20 uM by measuring LDH activity by cell based assay | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
9. | ALA4825142 | B | Inhibition of recombinant human AChE expressed in HEK293 cells by Ellman's method | Homo sapiens | 28 | cell-based format | Scientific Literature | ||
10. | ALA4825145 | B | Inhibition of recombinant equine BChE by Ellman's method | Equus caballus | 26 | single protein format | Scientific Literature | ||
11. | ALA4825148 | P | Solubility of the compound at >= 50 uM | 15 | small-molecule physicochemical format | Scientific Literature |