# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1065960 | B | Inhibition of human topoisomerase 2alpha-mediated kinetoplast DNA decatenation at 100 uM | Homo sapiens | 16 | single protein format | Scientific Literature | ||
2. | ALA1065962 | B | Induction of DNA intercalation in pRYG DNA at 100 uM by agarose gel electrophoresis | 18 | nucleic acid format | Scientific Literature | |||
3. | ALA1065963 | B | Inhibition of Xanthomonas vasicola XhoI assessed as pBSKS cleavage at 100 uM by endonuclease assay | Xanthomonas vasicola | 18 | single protein format | Scientific Literature | ||
4. | ALA1065964 | F | Growth inhibition of Saccharomyces cerevisiae BY4741 after 24 hrs | Saccharomyces cerevisiae | 12 | organism-based format | Scientific Literature | ||
5. | ALA3107976 | F | Cytotoxicity against wild-type human MDA-MB-231 cells after 5 days | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
6. | ALA3107977 | F | Cytotoxicity against human MDA-MB-231 cells overexpressing DT-diaphorase after 5 days | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
7. | ALA3107978 | F | Cytotoxicity against human MDA-MB-231 cells overexpressing NADPH-cytochrome P450 reductase after 5 days | Homo sapiens | 24 | cell-based format | Scientific Literature | ||
8. | ALA3107979 | F | Selectivity ratio of EC50 for wild-type human MDA-MB-231 cells to EC50 for human MDA-MB-231 cells overexpressing NADPH-cytochrome P450 reductase | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
9. | ALA3107980 | F | Cytotoxicity against wild-type human MDA-MB-231 cells treated for 4 hrs under aerobic condition followed by compound-washout incubated in drug-free media for 5 days under aerobic condition | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
10. | ALA3107981 | F | Cytotoxicity against wild-type human MDA-MB-231 cells treated for 4 hrs under anoxic condition followed by compound-washout incubated in drug-free media for 5 days under aerobic condition | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
11. | ALA3107982 | F | Ratio of EC50 for wild-type human MDA-MB-231 cells treated for 4 hrs under aerobic condition to EC50 for wild-type human MDA-MB-231 cells treated for 4 hrs under anoxic condition | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
12. | ALA3107983 | F | Cytotoxicity against human MDA-MB-231 cells overexpressing NADPH-cytochrome P450 reductase treated for 4 hrs under aerobic condition followed by compound-washout incubated in drug-free media for 5 days under aerobic condition | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
13. | ALA3108127 | F | Cytotoxicity against human MDA-MB-231 cells overexpressing NADPH-cytochrome P450 reductase treated for 4 hrs under anoxic condition followed by compound-washout incubated in drug-free media for 5 days under aerobic condition | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
14. | ALA3108128 | F | Ratio of EC50 for human MDA-MB-231 cells overexpressing NADPH-cytochrome P450 reductase treated for 4 hrs under aerobic condition to EC50 for human MDA-MB-231 cells overexpressing NADPH-cytochrome P450 reductase treated for 4 hrs under anoxic condition | Homo sapiens | 12 | cell-based format | Scientific Literature |