| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1819642 | B | Displacement of [3H]citalopram from human recombinant SERT scintillation proximity assay | Homo sapiens | 39 | single protein format | Scientific Literature | ||
| 2. | ALA1819643 | B | Displacement of [3H]nisoxetine from human recombinant NET by scintillation proximity assay | Homo sapiens | 39 | single protein format | Scientific Literature | ||
| 3. | ALA1819644 | B | Displacement of [3H]WIN-35428 from human recombinant DAT by scintillation proximity assay | Homo sapiens | 39 | single protein format | Scientific Literature | ||
| 4. | ALA1068886 | B | Displacement of [3H]WIN-35428 from human recombinant DAT expressed in BacMam virus-transduced cells by scintillation proximity assay | Homo sapiens | 51 | cell-based format | Scientific Literature | ||
| 5. | ALA1068887 | B | Displacement of [3H]nisoxetine from human recombinant NET expressed in BacMam virus-transduced cells by scintillation proximity assay | Homo sapiens | 51 | cell-based format | Scientific Literature | ||
| 6. | ALA1068888 | B | Displacement of [3H]citalopram from human recombinant SERT expressed in BacMam virus-transduced cells by scintillation proximity assay | Homo sapiens | 51 | cell-based format | Scientific Literature | ||
| 7. | ALA1068889 | B | Selectivity for human recombinant SERT over human recombinant DAT | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 8. | ALA1068894 | B | Displacement of [3H]citalopram from rat cortex SERT by filtration binding assay | Rattus norvegicus | 2 | assay format | Scientific Literature | ||
| 9. | ALA1068895 | A | Inhibition of human CYP1A2 by fluorescence assay | Homo sapiens | 9 | single protein format | Scientific Literature | ||
| 10. | ALA1068896 | A | Inhibition of human CYP2C9 by fluorescence assay | Homo sapiens | 9 | single protein format | Scientific Literature | ||
| 11. | ALA1068897 | A | Inhibition of human CYP2C19 by fluorescence assay | Homo sapiens | 9 | single protein format | Scientific Literature | ||
| 12. | ALA1068898 | A | Inhibition of human CYP2CD6 by fluorescence assay | Homo sapiens | 11 | single protein format | Scientific Literature | ||
| 13. | ALA1068899 | A | Inhibition of human CYP3A4 by fluorescence assay | Homo sapiens | 9 | single protein format | Scientific Literature | ||
| 14. | ALA1068900 | A | Intrinsic clearance in human liver microsomes assessed per gram of protein at 0.5 uM after 30 mins by HPLC-MS/MS analysis | Homo sapiens | 7 | microsome format | Scientific Literature | ||
| 15. | ALA1068901 | A | Intrinsic clearance in rat liver microsomes assessed per gram of protein at 0.5 uM after 30 mins by HPLC-MS/MS analysis | Rattus norvegicus | 7 | microsome format | Scientific Literature | ||
| 16. | ALA1068902 | A | Blood clearance in rat | Rattus norvegicus | 5 | organism-based format | Scientific Literature | ||
| 17. | ALA1068903 | A | Half life in rat | Rattus norvegicus | 5 | organism-based format | Scientific Literature | ||
| 18. | ALA1068904 | A | Volume of distribution in rat | Rattus norvegicus | 5 | organism-based format | Scientific Literature | ||
| 19. | ALA1068905 | A | Bioavailability in rat | Rattus norvegicus | 5 | organism-based format | Scientific Literature | ||
| 20. | ALA1068906 | A | Ratio of drug level in brain to blood in rat | Rattus norvegicus | 5 | tissue-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!