# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1070333 | F | Growth inhibition of human PC3 cells after 24 hrs by trypan blue exclusion method | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
2. | ALA1070334 | F | Cytotoxicity against human PC3 cells at 5 uM after 24 hrs by trypan blue exclusion method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
3. | ALA1070338 | F | Increase in RASSF1A gene expression in human PC3 cells at 5 uM after 3 days hrs by RT-PCR | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
4. | ALA1070340 | F | Decrease in RASSF1A gene expression in human PC3 cells at 5 uM after 3 days hrs by RT-PCR | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
5. | ALA1070342 | B | Inhibition of DNA methyltransferase activity in human PC3 cells at 2 uM after 3 days | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
6. | ALA2404102 | B | Binding affinity to DNA (unknown origin) assessed as induction of conformational changes at 100 uM after 2 hrs by CD spectrometric analysis | Not specified | 1 | assay format | Scientific Literature | ||
7. | ALA2404104 | B | Binding affinity to DNA minor groove (unknown origin) by ITC analysis | Not specified | 1 | assay format | Scientific Literature | ||
8. | ALA2404105 | B | Binding affinity to DNA (unknown origin) at 1 mM by fourier transform infrared spectroscopic analysis | Not specified | 1 | assay format | Scientific Literature | ||
9. | ALA2404106 | B | Binding affinity to DNA (unknown origin) after 2 hrs by UV-Vis absorption spectroscopic analysis | Not specified | 1 | assay format | Scientific Literature | ||
10. | ALA2404231 | B | Binding affinity to DNA (unknown origin) at 100 uM after 2 hrs by UV-Vis absorption spectroscopic analysis | Not specified | 4 | assay format | Scientific Literature | ||
11. | ALA2404240 | F | Induction of apoptosis in human PANC1 cells assessed as procaspase-9 cleavage at 25 uM after 24 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
12. | ALA2404241 | F | Induction of apoptosis in human PANC1 cells assessed as procaspase-8 cleavage at 25 uM after 24 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
13. | ALA2404242 | F | Induction of apoptosis in human T98G cells assessed as procaspase-9 cleavage at 25 uM after 24 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
14. | ALA2404243 | F | Induction of apoptosis in human PANC1 cells assessed as procaspase-7 cleavage at 25 uM after 24 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
15. | ALA2404244 | F | Induction of apoptosis in human T98G cells assessed as procaspase-8 cleavage at 25 uM after 24 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
16. | ALA2404248 | F | Downregulation of total Bid expression in human PANC1 cells at 25 uM after 24 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
17. | ALA2404250 | F | Downregulation of Bcl-xL expression in human PANC1 cells at 25 uM after 24 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
18. | ALA2404251 | F | Downregulation of total Bid expression in human T98G cells at 25 uM after 24 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
19. | ALA2404863 | F | Induction of mitochondrial transmembrane depolarization in human PANC1 cells at 30 uM after 24 hrs by JC1 staining-based flow cytometric analysis (Rvb = 2.7%) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
20. | ALA2404864 | F | Induction of apoptosis in human T98G cells assessed as procaspase-7 cleavage at 25 uM after 24 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature |