# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1072833 | B | Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assay | Homo sapiens | 40 | single protein format | Scientific Literature | ||
2. | ALA1072834 | P | Aqueous solubility of the compound | 40 | small-molecule physicochemical format | Scientific Literature | |||
3. | ALA1072835 | B | Inhibition of human recombinant SFRP1 expressed in human U2OS cells assessed as increase in Wnt signaling after 16 to 18 hrs by luciferase reporter gene assay | Homo sapiens | 40 | cell-based format | Scientific Literature | ||
4. | ALA1072836 | B | Inhibition of human recombinant SFRP1 expressed in human U2OS cells assessed as drug level required for twofold increase in Wnt signaling after 16 to 18 hrs by luciferase reporter gene assay | Homo sapiens | 40 | cell-based format | Scientific Literature | ||
5. | ALA1072837 | B | Inhibition of human recombinant SFRP1 expressed in human U2OS cells assessed as drug level required for fourfold increase in Wnt signaling after 16 to 18 hrs by luciferase reporter gene assay | Homo sapiens | 38 | cell-based format | Scientific Literature | ||
6. | ALA1072838 | P | Aqueous solubility at pH 7.4 | 18 | small-molecule physicochemical format | Scientific Literature | |||
7. | ALA1072839 | A | Half life in human liver microsomes at 1 uM | Homo sapiens | 17 | microsome format | Scientific Literature | ||
8. | ALA1072840 | A | Half life in rat liver microsomes at 1 uM | Rattus norvegicus | 18 | microsome format | Scientific Literature |