# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA615213 | B | Molar concentration needed to give 50% prevention of 2-5A (Adenosine dependent endoribonuclease) | 13 | ALA1122663 | single protein format | Scientific Literature | ||
2. | ALA615273 | B | Molar concentration required to displace 50% of the radiolabeled probe from 2-5A (Adenosine dependent endoribonuclease) in endonuclease-nitrocellulose complex | 17 | ALA1122663 | single protein format | Scientific Literature | ||
3. | ALA830037 | B | Effective concentration for activation of RNase L | 3 | ALA1137177 | assay format | Scientific Literature | ||
4. | ALA1065130 | B | Inhibition of human RNaseL ANK domain expressed in Escherichia coli assessed as 5' flurescein-r(C11U2C7)-3' RNA cleavage | Homo sapiens | 6 | ALA1157739 | assay format | Scientific Literature | |
5. | ALA1065131 | B | Inhibition of human RNaseL ANK domain expressed in Escherichia col assessed as 5' flurescein-r(C11U2C7)-3' RNA cleavage relative to control | Homo sapiens | 6 | ALA1157739 | assay format | Scientific Literature | |
6. | ALA1065132 | P | Stability assessed as half life | 5 | ALA1157739 | small-molecule physicochemical format | Scientific Literature | ||
7. | ALA2060468 | B | Activation of human RNase L expressed in Escherichia coli BL21 (DE3) cells assessed as RNA cleavage using Cy5-rC11-UU-C7-BHQ2 as substrate by FRET assay | Homo sapiens | 22 | ALA2057064 | cell-based format | Scientific Literature | |
8. | ALA3820072 | F | Cytotoxicity against human HeLa cells assessed as cell growth inhibition at 0.1 to 1 uM after 6 to 24 hrs by counting chamber analysis | Homo sapiens | 1 | ALA3817765 | cell-based format | Scientific Literature | |
9. | ALA3820073 | A | Half life of the compound assessed as snake venom phosphodiesterase-mediated compound hydrolysis at 9 uM by HPLC analysis | Serpentes | 2 | ALA3817765 | assay format | Scientific Literature | |
10. | ALA3820074 | B | Induction of recombinant human RNase L activity expressed in Escherichia coli using F-5'-r(C11U2C7)-3' as substrate by polyacrylamide gel electrophoresis | Homo sapiens | 9 | ALA3817765 | assay format | Scientific Literature |