| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1069446 | P | Partition coefficient, log P by RP-HPLC | 12 | ALA1159065 | small-molecule physicochemical format | Scientific Literature | ||
| 2. | ALA1069447 | P | Partition coefficient, log P by shake flask method | 14 | ALA1159065 | small-molecule physicochemical format | Scientific Literature | ||
| 3. | ALA1069448 | P | Partition coefficient, log P in presence of Fe(3+) by RP-HPLC | 10 | ALA1159065 | small-molecule physicochemical format | Scientific Literature | ||
| 4. | ALA1069449 | T | Toxicity in MDCK cells by MTT method | Canis lupus familiaris | 11 | ALA1159065 | cell-based format | Scientific Literature | |
| 5. | ALA1069450 | T | Toxicity in human SK-N-MC cells by MTT method | Homo sapiens | 11 | ALA1159065 | cell-based format | Scientific Literature | |
| 6. | ALA1069452 | F | Induction of [59Fe] mobilization in human SK-N-MC cells prelabeled with [59Fe]transferrin at 50 uM after 3 hrs relative to desferrioxamine B | Homo sapiens | 3 | ALA1159065 | cell-based format | Scientific Literature | |
| 7. | ALA1069453 | B | Inhibition of [59Fe] uptake from [59Fe]transferrin in human SK-N-MC cells assessed as at 50 uM after 3 hrs relative to untreated control | 4 | ALA1159065 | cell-based format | Scientific Literature | ||
| 8. | ALA1069454 | B | Inhibition of [59Fe] uptake from [59Fe]transferrin in human SK-N-MC cells at 50 uM after 3 hrs relative to relative to desferrioxamine B | 5 | ALA1159065 | cell-based format | Scientific Literature | ||
| 9. | ALA4185264 | P | Octanol-water partition coefficient, log P of the compound at 1 mg by RP-HPLC analysis | 21 | ALA4184139 | small-molecule physicochemical format | Scientific Literature | ||
| 10. | ALA4185265 | F | Cytoprotection against PQ-induced cell death in human SK-N-BE(2)-M17 cells assessed as increase in cell viability at 100 uM pretreated for 2 hrs followed by 1 mM PQ addition measured after 24 hrs by MTT assay | Homo sapiens | 16 | ALA4184139 | cell-based format | Scientific Literature | |
| 11. | ALA4185266 | F | Cytoprotection against PQ-induced cell death in human SK-N-BE(2)-M17 cells assessed as increase in cell viability at 100 uM pretreated for 2 hrs followed by 1 mM PQ addition measured after 24 hrs by LDH assay | Homo sapiens | 16 | ALA4184139 | cell-based format | Scientific Literature | |
| 12. | ALA4185267 | F | Cytoprotection against H2O2-induced cell death in human SK-N-BE(2)-M17 cells assessed as increase in cell viability at 100 uM pretreated for 2 hrs followed by 1 mM H2O2 addition measured after 24 hrs by MTT assay | Homo sapiens | 16 | ALA4184139 | cell-based format | Scientific Literature | |
| 13. | ALA4185268 | F | Cytoprotection against H2O2-induced cell death in human SK-N-BE(2)-M17 cells assessed as increase in cell viability at 100 uM pretreated for 2 hrs followed by 1 mM H2O2 addition measured after 24 hrs by LDH assay | Homo sapiens | 16 | ALA4184139 | cell-based format | Scientific Literature | |
| 14. | ALA4185269 | F | Cytoprotection against PQ-induced cell death in human SK-N-BE(2)-M17 cells assessed as increase in cell viability at 100 uM treated 2 hrs post 2 mM PQ treatment measured after 24 hrs by MTT assay | Homo sapiens | 15 | ALA4184139 | cell-based format | Scientific Literature | |
| 15. | ALA4185271 | F | Cytoprotection against H2O2-induced cell death in human SK-N-BE(2)-M17 cells assessed as increase in cell viability at 100 uM treated 2 hrs post 0.8 mM H2O2 treatment measured after 24 hrs by MTT assay | Homo sapiens | 14 | ALA4184139 | cell-based format | Scientific Literature | |
| 16. | ALA4185273 | F | Cytoprotection against PQ-induced cell death in human SK-N-BE(2)-M17 cells assessed as increase in cell viability treated 2 hrs post 2 mM PQ treatment measured after 24 hrs by MTT assay | Homo sapiens | 6 | ALA4184139 | cell-based format | Scientific Literature | |
| 17. | ALA4185275 | F | Cytoprotection against PQ-induced cell death in human SK-N-BE(2)-M17 cells assessed as increase in cell viability at 100 uM treated post 200 uM Fecl3 and 1 mM PQ treatment measured after 24 hrs by MTT assay | Homo sapiens | 9 | ALA4184139 | cell-based format | Scientific Literature | |
| 18. | ALA4185276 | F | Cytoprotection against PQ-induced cell death in human SK-N-BE(2)-M17 cells assessed as increase in cell viability at 100 uM treated post 200 uM Fecl3 and 1 mM PQ treatment measured after 24 hrs by LDH assay | Homo sapiens | 8 | ALA4184139 | cell-based format | Scientific Literature | |
| 19. | ALA4185277 | F | Cytoprotection against H2O2-induced cell death in BSO pretreated C57BL6/J mouse brain primary astrocytes assessed as increase in cell viability at 10 uM pretreated for 2 hrs followed by H2O2 addition measured after 24 hrs by MTT assay | Mus musculus | 10 | ALA4184139 | cell-based format | Scientific Literature | |
| 20. | ALA4185278 | F | Cytoprotection against H2O2-induced cell death in BSO pretreated C57BL6/J mouse brain primary astrocytes assessed as increase in cell viability at 10 uM pretreated for 2 hrs followed by H2O2 addition measured after 24 hrs by LDH release assay | Mus musculus | 8 | ALA4184139 | cell-based format | Scientific Literature |
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