| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1069455 | B | Inhibition of human recombinant SIRT1 by Flour de Lys assay | Homo sapiens | 12 | ALA1159066 | single protein format | Scientific Literature | |
| 2. | ALA1069456 | B | Inhibition of human recombinant SIRT2 by Flour de Lys assay | Homo sapiens | 12 | ALA1159066 | single protein format | Scientific Literature | |
| 3. | ALA1069461 | F | Protection against mutant PABPN1-induced toxicity in transgenic Caenorhabditis elegans coexpressing nuclear GFP and PABPN1-A13 assessed as inhibition of nuclear collapse at 11.1 uM | Caenorhabditis elegans | 1 | ALA1159066 | organism-based format | Scientific Literature | |
| 4. | ALA1069462 | F | Protection against mutant PABPN1-induced toxicity in transgenic Caenorhabditis elegans coexpressing nuclear GFP and PABPN1-A13 assessed as inhibition of deffective worm motility at 11.1 uM | Caenorhabditis elegans | 1 | ALA1159066 | organism-based format | Scientific Literature | |
| 5. | ALA1069466 | F | Effect on nuclear integrity in transgenic Caenorhabditis elegans coexpressing nuclear GFP and normal PABPN1-A10 | Caenorhabditis elegans | 8 | ALA1159066 | organism-based format | Scientific Literature | |
| 6. | ALA1799828 | F | Cell cycle arrest in human U937 cells assessed as accumulation at G2/M phase at 50 uM incubated for 30 hrs by flow cytometry | Homo sapiens | 2 | ALA1795290 | cell-based format | Scientific Literature | |
| 7. | ALA1799831 | B | Inhibition of human recombinant SIRT2 expressed in Escherichia coli incubated at 37 degC for 2 hrs by Fluor de Lys fluorescence assay | Homo sapiens | 8 | ALA1795290 | assay format | Scientific Literature | |
| 8. | ALA1799832 | B | Inhibition of human recombinant SIRT1 expressed in Escherichia coli incubated at 37 degC for 2 hrs by Fluor de Lys fluorescence assay | Homo sapiens | 8 | ALA1795290 | assay format | Scientific Literature | |
| 9. | ALA1799833 | B | Inhibition of human recombinant SIRT2 expressed in Escherichia coli at 50 uM incubated at 37 degC for 2 hrs by Fluor de Lys fluorescence assay | Homo sapiens | 39 | ALA1795290 | assay format | Scientific Literature | |
| 10. | ALA1799834 | B | Inhibition of human recombinant SIRT1 expressed in Escherichia coli at 50 uM incubated at 37 degC for 2 hrs by Fluor de Lys fluorescence assay | Homo sapiens | 39 | ALA1795290 | assay format | Scientific Literature | |
| 11. | ALA1799836 | F | Induction of granulocytic differentiation in human U937 cells assessed as change in CD11c expression at 50 uM incubated for 30 mins by FACS assay | Homo sapiens | 27 | ALA1795290 | cell-based format | Scientific Literature | |
| 12. | ALA2175634 | F | Cytotoxicity against human CRO cells after 72 hrs by Cell-titer GLo assay | Homo sapiens | 4 | ALA2169828 | cell-based format | Scientific Literature | |
| 13. | ALA2175635 | F | Cytotoxicity against human CRC 1.1 after 72 hrs by Cell-titer GLo assay | Homo sapiens | 4 | ALA2169828 | assay format | Scientific Literature | |
| 14. | ALA2175636 | F | Cytotoxicity against human 30P cells after 72 hrs by Cell-titer GLo assay | Homo sapiens | 5 | ALA2169828 | cell-based format | Scientific Literature | |
| 15. | ALA2175637 | F | Cytotoxicity against human 30PT cells after 72 hrs by Cell-titer GLo assay | Homo sapiens | 5 | ALA2169828 | cell-based format | Scientific Literature | |
| 16. | ALA2175757 | F | Induction of apoptosis in human U937 cell at 50 uM after 30 hrs by annexin V-FITC/ propidium iodide staining based flow cytometry analysis | Homo sapiens | 6 | ALA2169828 | cell-based format | Scientific Literature | |
| 17. | ALA2176205 | B | Inhibition of human recombinant SIRT2 expressed in Escherichia coli cells using Z-MAL substrate after 4 hrs by fluorescence assay | Homo sapiens | 1 | ALA2169828 | cell-based format | Scientific Literature | |
| 18. | ALA2176206 | B | Inhibition of human recombinant SIRT2 expressed in Escherichia coli using Fluor de Lys substrate by fluorescence assay | Homo sapiens | 1 | ALA2169828 | assay format | Scientific Literature | |
| 19. | ALA2176207 | B | Inhibition of human recombinant SIRT2 expressed in Escherichia coli cells using acetylated Lys side chain amino acids 379-382 (Arg-His-Lys-Lys(Ac)) p53 conjugated with aminomethylcoumarin as substrate by fluorescence assay | Homo sapiens | 15 | ALA2169828 | cell-based format | Scientific Literature | |
| 20. | ALA2176208 | B | Inhibition of human recombinant SIRT1 expressed in Escherichia coli cells using acetylated Lys side chain amino acids 379-382 (Arg-His-Lys-Lys(Ac)) p53 conjugated with aminomethylcoumarin as substrate by fluorescence assay | Homo sapiens | 14 | ALA2169828 | cell-based format | Scientific Literature |
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