# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA753513 | B | Compound was tested for the binding affinity towards recombinant NBD2 C-terminal cytotoxic nucleotide-binding domain of mouse P-Glycoprotein | 10 | ALA1132759 | single protein format | Scientific Literature | ||
2. | ALA846982 | F | Change in Fmax was determined | 7 | ALA1132759 | assay format | Scientific Literature | ||
3. | ALA1035259 | B | Inhibition of MRP1 | 1 | ALA1158473 | single protein format | Scientific Literature | ||
4. | ALA1046412 | F | Antioxidant activity assessed as DPPH radical scavenging activity at 50 uM after 30 mins by spectrophotometry | 4 | ALA1155967 | assay format | Scientific Literature | ||
5. | ALA1046416 | F | Inhibition of lipid peroxidation in Sprague-Dawley rat liver homogenate assessed as malondialdehyde formation after 1 hr by TBARS assay | Rattus norvegicus | 19 | ALA1155967 | tissue-based format | Scientific Literature | |
6. | ALA1046420 | F | Iron chelating activity assessed as inhibition of ferrozine-Fe2+ complex formation at 150 uM after 10 mins by spectrophotometry | 9 | ALA1155967 | assay format | Scientific Literature | ||
7. | ALA1046421 | F | Iron chelating activity assessed as inhibition of ferrozine-Fe2+ complex formation after 10 mins by spectrophotometry | 11 | ALA1155967 | assay format | Scientific Literature | ||
8. | ALA1046423 | F | Neuroprotective activity against H2O2-induced injury in rat PC12 cells assessed as increase in cell viability at 50 uM treated 2 hrs before H2O2 challenge measured after 4 hrs by MTT assay | Rattus norvegicus | 9 | ALA1155967 | cell-based format | Scientific Literature | |
9. | ALA1046424 | F | Neuroprotective activity against H2O2-induced injury in rat PC12 cells treated 2 hrs before H2O2 challenge measured after 4 hrs by MTT assay | Rattus norvegicus | 8 | ALA1155967 | cell-based format | Scientific Literature | |
10. | ALA1046426 | B | Inhibition of rat liver xanthine oxidase after 2 hrs by spectrophotometry | Rattus norvegicus | 4 | ALA1155967 | assay format | Scientific Literature | |
11. | ALA1809958 | F | Antioxidant activity in rat immortalized Rat1 cells assessed as inhibition of hydrogen peroxide-induced reactive oxygen species production by measuring conversion of 2',7'-dichlorofluorescin diacetate into 2',7'-dichlorofluorescein at 30 uM treated 48 hrs before H2O2 challenge measured after 15 mins by fluorescence assay | Rattus norvegicus | 11 | ALA1806413 | cell-based format | Scientific Literature | |
12. | ALA1809959 | P | Octanol-water partition coefficient, log P of the compound at pH 7.4 by stir-flask method | 11 | ALA1806413 | small-molecule physicochemical format | Scientific Literature | ||
13. | ALA1809960 | A | Cytotoxicity against rat immortalized Rat1 cells after 48 hrs by MTT assay | Rattus norvegicus | 11 | ALA1806413 | cell-based format | Scientific Literature | |
14. | ALA1810029 | A | Cytotoxicity against rat immortalized Rat1 cells assessed as reduction of cell viability at 30 uM after 48 hrs by MTT assay | Rattus norvegicus | 11 | ALA1806413 | cell-based format | Scientific Literature | |
15. | ALA1963981 | F | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) | 41,327 | ALA1201862 | cell-based format | PubChem BioAssays | ||
16. | ALA1963985 | F | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | 41,631 | ALA1201862 | cell-based format | PubChem BioAssays | ||
17. | ALA1963989 | F | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) | 41,040 | ALA1201862 | cell-based format | PubChem BioAssays | ||
18. | ALA1963990 | F | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) | 40,970 | ALA1201862 | cell-based format | PubChem BioAssays | ||
19. | ALA1963991 | F | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | 36,454 | ALA1201862 | cell-based format | PubChem BioAssays | ||
20. | ALA1963994 | F | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) | 37,749 | ALA1201862 | cell-based format | PubChem BioAssays |