# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1074776 | B | Displacement of [3H]rosiglitazone from rat liver mitochondrial mitoNEET by scintillation counting | Rattus norvegicus | 3 | ALA1156847 | assay format | Scientific Literature | |
2. | ALA1074777 | F | Inhibition of respiration in Sprague-Dawley rat mitochondria assessed as reduction in respiratory control rate | Rattus norvegicus | 1 | ALA1156847 | mitochondrion format | Scientific Literature | |
3. | ALA1074778 | F | Reduction in state 3 respiration in Sprague-Dawley rat mitochondria | Rattus norvegicus | 1 | ALA1156847 | mitochondrion format | Scientific Literature | |
4. | ALA1074779 | F | Neuroprotective activity against rotenone-induced cell death in human SH-SY5Y assessed as reduction in LDH release pretreated 1 hrs before rotenone challenge measured after 24 hrs | Homo sapiens | 1 | ALA1156847 | cell-based format | Scientific Literature | |
5. | ALA1074780 | F | Neuroprotective activity against rotenone-induced cell death in human SH-SY5Y assessed as reduction in LDH release pretreated 1 hrs before rotenone challenge measured after 24 hrs relative to control | Homo sapiens | 1 | ALA1156847 | cell-based format | Scientific Literature | |
6. | ALA1817009 | B | Inhibition of human recombinant MAOB by amplex red assay | Homo sapiens | 25 | ALA1811826 | single protein format | Scientific Literature | |
7. | ALA1817010 | B | Inhibition of human recombinant MAOA assessed as inhibition of kynuramine conversion to fluorescent metabolite 4-hydroxyquinoline by fluorimetry | Homo sapiens | 25 | ALA1811826 | single protein format | Scientific Literature | |
8. | ALA1817107 | F | Neuroprotective activity in MPTP-stimulated C57BL/6 mouse assessed as increase in striatal dopamine content at 10 mg/kg, sc administered 1 hr before MPTP challenge measured after 7 days by HPLC method | Mus musculus | 1 | ALA1811826 | organism-based format | Scientific Literature | |
9. | ALA1817108 | T | Toxicity in C57BL/6 mouse assessed as striatal dopamine level at 10 mg/kg, sc measured after 7 days by HPLC method | Mus musculus | 1 | ALA1811826 | organism-based format | Scientific Literature | |
10. | ALA1826572 | B | Displacement of [3H]-rosiglitazone from human recombinant C-terminal His-tagged cytosolic domain of mitoNEET (32-108) by scintillation proximity assay | Homo sapiens | 21 | ALA1821631 | single protein format | Scientific Literature | |
11. | ALA3863230 | B | Displacement of [3H]rosiglitazone from recombinant human C-terminal His-tagged MitoNEET cytosolic domain (32 to 108 residues) expressed in Escherichia coli BL21 by scintillation proximity assay | Homo sapiens | 86 | ALA3862005 | assay format | Scientific Literature | |
12. | ALA3863231 | B | Displacement of [3H]rosiglitazone from recombinant human C-terminal His-tagged MitoNEET cytosolic domain (32 to 108 residues) expressed in Escherichia coli BL21 by Cheng-Prusoff analysis | Homo sapiens | 86 | ALA3862005 | assay format | Scientific Literature | |
13. | ALA4370834 | B | Binding affinity to recombinant human N-terminal His6-tagged NAF1 expressed in Escherichia coli by scintillation proximity assay | Homo sapiens | 3 | ALA4368935 | assay format | Scientific Literature | |
14. | ALA4370835 | B | Binding affinity to NAF1 (unknown origin) expressed in human HepG2 cells assessed as inhibition of mitochondrial respiration at 30 uM | Homo sapiens | 3 | ALA4368935 | cell-based format | Scientific Literature | |
15. | ALA4370836 | B | Binding affinity to NAF1 in human HepG2 cells assessed as inhibition of mitochondrial respiration at 30 uM | Homo sapiens | 3 | ALA4368935 | cell-based format | Scientific Literature |